Introduction: Hemicorporectomy progresses with hemodynamic and ventilatory repercussions that make anesthesia management definitive to patient outcome.
Objective: Report anesthesia approach for a patient with squamous cell carcinoma submitted to urgent hemicorporectomy after an episode of hypovolemic shock.
Case Report: After lesion bleeding, the patient presented hypovolemic shock class 3, and was submitted to urgent procedure under general inhalation anesthesia and intravenous multimodal analgesia, presenting hemodynamic instability requiring massive blood transfusion after spinal cord transection and removal of surgical specimen.