Publications by authors named "Rose Antony"

Article Synopsis
  • The study created a comprehensive reference atlas of human prenatal skin (7-17 weeks post-conception) using advanced techniques like single-cell and spatial transcriptomics to explore the roles of immune cells, specifically macrophages, in skin development.
  • It was found that interactions between immune and non-immune cells are essential for key processes in skin development, such as hair follicle formation, scarless wound healing, and blood vessel growth.
  • Additionally, while a skin organoid model mimicked certain features of prenatal skin, it lacked immune cells and showed limited blood vessel diversity, highlighting the important roles of macrophages and their derived factors in skin morphology and development.
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The extraembryonic yolk sac (YS) ensures delivery of nutritional support and oxygen to the developing embryo but remains ill-defined in humans. We therefore assembled a comprehensive multiomic reference of the human YS from 3 to 8 postconception weeks by integrating single-cell protein and gene expression data. Beyond its recognized role as a site of hematopoiesis, we highlight roles in metabolism, coagulation, vascular development, and hematopoietic regulation.

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Unlabelled: The existing research on fresh food supply chains (FFSC) sustainability consisting of fur fundamental pillars, namely green (G), resilient (R), agile (A), and sustainability (S) (hereafter GRAS), is explored sparsely and needs thorough investigation. Further, conceptualization and mutual interactions among GRAS enablers that can help perpetuate sustainable supply chains (SSC) still need to be addressed. This study proposes a methodological framework to evaluate the SCS from the perspective of GRAS enablers with an application for the Indian FFSC.

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Ethnopharmacological Relevance: India is having a rich vegetation with a wide variety of plants, because of the extreme variations in geographical and climatic conditions prevailing in the country. Plants have been used since ancient times for the treatment of various ailments. Especially, Kani tribal communities in Thodu hills of Kerala meet their healthcare needs by using non-timber minor forest products and preparations based on traditional knowledge.

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