The extraembryonic yolk sac (YS) ensures delivery of nutritional support and oxygen to the developing embryo but remains ill-defined in humans. We therefore assembled a comprehensive multiomic reference of the human YS from 3 to 8 postconception weeks by integrating single-cell protein and gene expression data. Beyond its recognized role as a site of hematopoiesis, we highlight roles in metabolism, coagulation, vascular development, and hematopoietic regulation.
View Article and Find Full Text PDFUnlabelled: The existing research on fresh food supply chains (FFSC) sustainability consisting of fur fundamental pillars, namely green (G), resilient (R), agile (A), and sustainability (S) (hereafter GRAS), is explored sparsely and needs thorough investigation. Further, conceptualization and mutual interactions among GRAS enablers that can help perpetuate sustainable supply chains (SSC) still need to be addressed. This study proposes a methodological framework to evaluate the SCS from the perspective of GRAS enablers with an application for the Indian FFSC.
View Article and Find Full Text PDFEthnopharmacological Relevance: India is having a rich vegetation with a wide variety of plants, because of the extreme variations in geographical and climatic conditions prevailing in the country. Plants have been used since ancient times for the treatment of various ailments. Especially, Kani tribal communities in Thodu hills of Kerala meet their healthcare needs by using non-timber minor forest products and preparations based on traditional knowledge.
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