Publications by authors named "Rosario Torres Iberico"
Objective: Atopic dermatitis is a chronic, systemic, relapsing disease with dermatological manifestations, which imposes a high burden on patients, families and the health care system and has a high psychological, social, and economic impact and on the quality of life of patients. It mainly affects the pediatric population and, to a lesser extent, the adult population. The clinical presentation varies according to the age and evolution of the disease, and currently there are multiple pharmacological and non-pharmacological therapies available for the symptomatic management of patients.
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- Acquired epidermolysis bullosa is a rare autoimmune skin condition that affects children, characterized by autoantibodies against type VII collagen.
- A 12-year-old girl with bullous skin lesions was diagnosed through histopathological and immunofluorescence studies confirming the disease.
- Treatment with corticosteroids and dapsone showed positive results, highlighting the importance of early diagnosis and timely intervention to prevent lasting damage.
Background: Epidermolysis bullosa (EB) is a complex and heterogeneous dermatological disease. Four main types of EB have been described, each of them with distinct characteristics: EB simplex (EBS), dystrophic EB (DEB), junctional EB (JEB) and Kindler EB (KEB). Each main type varies in its manifestations, severity, and genetic abnormality.
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- Palisaded neutrophilic granulomatous dermatitis is a rare skin condition in children linked to autoimmune diseases, with its exact cause not fully understood but potentially involving immune complex deposition.
- An 11-year-old girl with polymorphic skin lesions and polyarthralgia was diagnosed with systemic lupus erythematosus and lupus nephritis, necessitating various treatments including steroids and immunosuppressants.
- Recognizing this skin condition is crucial as it may be an early indicator of systemic lupus erythematosus in young patients.
Article Synopsis
- The study at Instituto Nacional de Salud (INSN) analyzed clinical and epidemiological features of 93 patients diagnosed with epidermolysis bullosa (EB) from 1993 to 2015, focusing on their age, gender, and clinical forms.
- The majority of the patients were young boys, with dystrophic EB being the most common type, followed by simple, union, and Kindler syndrome.
- The research highlighted significant extrcutaneous complications, such as gastrointestinal and nutritional issues, and identified a considerable prevalence of malnutrition and anemia among the patients, with a reported mortality rate of 6.5%.