Currently, the high demand for new products in the automotive sector requires large investments in factories. The automotive industry is characterized by high automatization, largely achieved by manipulator robots capable of multitasking. This work presents a method for the optimization of trajectories in robots with six degrees of freedom and a spherical wrist.
View Article and Find Full Text PDFBackground: Human pythiosis, caused primarily by the aquatic oomycete, Pythium insidiosum, is an emerging but uncommon infection in North America. The infection is frequently life-threatening and is often initially unrecognized due to its rarity and similar presentation to certain fungal infections.
Methods: We report a case of skin and soft tissue pythiosis in a patient without significant underlying comorbidities acquired in a New Mexico hot spring and review its successful treatment.
Electromyography (EMG) signals are biomedical signals that measure electrical currents generated during muscle contraction. These signals are strongly influenced by physiological and anatomical characteristics of the muscles and represent the neuromuscular activities of the human body. The evolution of EMG analysis and acquisition techniques makes this technology more reliable for production engineering applications, overcoming some of its inherent issues.
View Article and Find Full Text PDFThis study is focused on the application of a cooling compressed air system in drilling processes; this environmentally friendly technique allows removing material at very low temperatures, approximately up to -22 °C in the cutting area. The main goals are to find the most improve cutting conditions with less energy consumption, for the drilling of reinforced polyether-ether-ketone with glass fiber at 30% (PEEK-GF30) with cooling compressed air by a Ranque-Hilsch vortex tube, and to find a balance between environmental conditions and adequate process performance. Drilling tests were carried out on plates of PEEK-GF30 to analyze the influence of cutting parameters and environmental temperature (-22, 0 and 22 °C) on variables such as thrust forces, energy and material removed rate by the use of statistical methods; analysis of variance, analysis of means, response surface, and desirability function were employed to identify the optimum region that provides the most improved values of the aforementioned variables.
View Article and Find Full Text PDFMelatonin is synthesized from serotonin and it is excreted as sulphatoxymelatonin in urine. We aim to evaluate urinary sulphatoxymelatonin as a biomarker of brain serotonin status in a cohort of patients with mutations in genes related to serotonin biosynthesis. We analized urinary sulphatoxymelatonin from 65 healthy subjects and from 28 patients with genetic defects.
View Article and Find Full Text PDFThe rapid analysis of genomic data is providing effective mutational confirmation in patients with clinical and biochemical hallmarks of a specific disease. This is the case for nonketotic hyperglycinemia (NKH), a Mendelian disorder causing seizures in neonates and early-infants, primarily due to mutations in the GLDC gene. However, understanding the impact of missense variants identified in this gene is a major challenge for the application of genomics into clinical practice.
View Article and Find Full Text PDFCoordinate measuring machines (CMM) are main instruments of measurement in laboratories and in industrial quality control. A compensation error model has been formulated (Part I). It integrates error and uncertainty in the feature measurement model.
View Article and Find Full Text PDFThe development of an error compensation model for coordinate measuring machines (CMMs) and its integration into feature measurement is presented. CMMs are widespread and dependable instruments in industry and laboratories for dimensional measurement. From the tip probe sensor to the machine display, there is a complex transformation of probed point coordinates through the geometrical feature model that makes the assessment of accuracy and uncertainty measurement results difficult.
View Article and Find Full Text PDFCase Rep Gastrointest Med
September 2016
Burkitt's lymphoma is a very aggressive type of B-cell NHL with replication approaching 100%. Primary gastrointestinal lymphoma is rare. In our case, a 24-year-old male initially presented with symptomatic anemia.
View Article and Find Full Text PDFThis paper presents a study of hole quality and energy consumption in the process of drilling a thermoplastic polymeric material, polyether-ether-ketone, reinforced with 30% glass fibers (PEEK-GF30). PEEK-GF30's capacity to be machined has focused on turning operations. Studies of drilling involving thermoplastic polymeric materials have considered materials with other types of matrices, or reinforcement.
View Article and Find Full Text PDFBackground: Musculoskeletal disorders (MSDs) that result from poor ergonomic design are one of the occupational disorders of greatest concern in the industrial sector. A key advantage in the primary design phase is to focus on a method of assessment that detects and evaluates the potential risks experienced by the operative when faced with these types of physical injuries. The method of assessment will improve the process design identifying potential ergonomic improvements from various design alternatives or activities undertaken as part of the cycle of continuous improvement throughout the differing phases of the product life cycle.
View Article and Find Full Text PDFBackground: The use of high-risk human papillomavirus (HRHPV) testing in the triage of women with a cytologic diagnosis of atypical squamous cells of undetermined significance (ASC-US) has gained widespread acceptance. To date, very little has been reported on the significance of the detection of HRHPV in elderly women.
Methods: Results of HRHPV testing performed on women aged > or =50 years were examined for a 20-month period.