Publications by authors named "Rosanun Sikarinkul"
This study compared the long-term outcome of different epithelial transplantation techniques to treat limbal stem cell deficiency (LSCD). We conducted a retrospective 15-year comparative systematic cohort study of patients with LSCD who underwent either cultivated limbal epithelial transplantation (CLET), simple limbal epithelial transplantation (SLET), or cultivated oral mucosal epithelial transplantation (COMET). We reviewed the demographic data, etiology, LSCD severity, best-corrected visual acuity, surgical outcomes, and complications.
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- * Out of 12 patients analyzed, only 25% had detectable donor cells after a mean follow-up of 55.3 months, with all successful cases occurring in those who underwent allo-SLET.
- * The findings suggest that while donor cells can survive long-term, their presence is not the sole factor in graft success, as the recipient's own cells seem to play a crucial role in repopulation, especially in partial cases of limbal stem cell deficiency.
Efficacy and outcome of simple limbal epithelial transplantation for limbal stem cell deficiency verified by epithelial phenotypes integrated with clinical evaluation.
Ocul Surf
October 2021
Purpose: To evaluate the efficacy and outcome of simple limbal epithelial transplantation (SLET) for limbal stem cell deficiency (LSCD) using epithelial phenotype detection integrated with clinical manifestation.
Methods: This prospective multicenter study included patients with LSCD who underwent autologous SLET (autoSLET) and living-related allogenic SLET (Lr-alloSLET). All patients were assessed by slit-lamp biomicroscopy, in vivo confocal microscopy (IVCM), and impression cytology with immunofluorescence staining (ICIF) before and after surgery.