Clinical Manifestations.

Background: Despite being off-label, antipsychotics and antidepressants are widely prescribed to manage Behavioural and Psychological Symptoms of Dementia (BPSD). Aim of our study was to assess the evolution of BPSD and psychoactive pharmacological therapy in older patients with dementia.

Method: In this retrospective observational study, outpatients with dementia underwent a Comprehensive Geriatric Assessment (ADL, IADL, CFS and CIRS), at baseline, 6-month and 12-month follow-up visits.

Clinical Manifestations.

Background: Behavioral and psychological symptoms of dementia (BPSD) can lead to loss of independence, increased risk of hospitalization and early institutionalization. This work aims to evaluate the relationship between physical performance and BPSD in older patients with dementia.

Method: In this observational single-center study, patients with dementia underwent a Comprehensive Geriatric Assessment (ADL, IADL, CIRS, CFS) and cognitive and neuropsychiatric evaluation (MMSE, NPI).

Frailty and Behavioral and Psychological Symptoms of Dementia: A Single Center Study.

During the time-course of cognitive decline, Behavioral and Psychological Symptoms of Dementia (BPSD) may arise, negatively impacting the outcomes. The aim of this single center, longitudinal study was to evaluate the correlation between frailty and BPSD in a population of older patients with dementia. BPSD were classified into three clusters: "mood/apathy" (depression, apathy, sleep disturbances, appetite disturbances), "psychosis" (delusions, hallucinations, and anxiety), and "hyperactivity" (agitation, elation, motor aberrant behavior, irritability, disinhibition).