Small RNAs and tooth development: The role of microRNAs in tooth agenesis and impaction.

Background/purpose: Tooth development, or odontogenesis, is a complex process in which several molecular pathways play a key role. Recently, microRNAs, a class of approximately 20-nucleotide small RNA molecules that regulate gene expression, have been implicated in the odontogenesis process. This study aimed to assess the role of miRNAs in odontogenesis anomalies, specifically agenesis and impaction.

The Use of CAD/CAM Technology in Mandibular Canine Disimpaction: A Case Report.

This case report of an 11-year-old subject shows the digital workflow for the management of an impacted mandibular canine using Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) technology along with Temporary Anchorage Devices (TADs). The miniscrew insertion site was planned using software, and a surgical guide was digitally designed and 3D printed. Orthodontic traction was performed using a 3D-designed and -printed device.

Local factors relating to mandibular canine impaction: A retrospective study.

Introduction: This study aimed to investigate the characteristics of impacted and transmigrated mandibular canines and the association existing between them and some local factors, such as degrees of axial inclination of mandibular incisors, skeletal Class, and mandibular symphysis width.

Methods: A retrospective observational study was performed on the medical records and radiographic examination (panoramic radiographs and lateral cephalograms) of 102 orthodontic patients divided into a study group, with at least 1 impacted mandibular canine (51 subjects) and a control group, without mandibular impaction (51 subjects). A chi-square test, t test, and analysis of variance test analysis were used to analyze the data.

Can computer-guided surgery help orthodontics in miniscrew insertion and corticotomies? A narrative review.

Orthodontics has considerably increased the use of technology combined with surgery as a tool to improve dental movements in terms of predictability, acceleration of movement, and fewer side effects. To achieve these goals miniscrews and corticotomy were introduced. The digital workflow permits an increase in the accuracy of surgical and orthodontic setups.

Predictive Analysis of Maxillary Canine Impaction through Bridging, Calcification, and Lateral Incisor Anomalies: A Retrospective Observational Study.

Maxillary canine impaction is an increasing dental anomaly and is often related to other dento-skeletal anomalies. The aim of this work is to support the clinician in evaluating the relationship between a displaced maxillary canine and clinical (the features of lateral incisors)/skeletal ( and bridging) anomalies through orthopanoramic radiographs, lateral cephalograms, and plaster casts to identify the parameters that best predict maxillary canine impaction. A retrospective observational study was carried out on the analysis of the medical records, radiographic findings (panoramic radiographs and lateral cephalograms), and plaster casts of 203 orthodontic patients divided into a case group, with at least one impacted maxillary canine, and a control group, without an impaction.

Evaluation of nasal airway resistance in a cohort of children with primary snoring and maxillary deficiency.

Background: The aim of this study was to test whether rapid palatal expansion is effective to improve nasal airway patency in a sample of pediatric patients with primary snoring.

Methods: A group of 21 subjects, 11 girls (52%) and 10 boys (48%), with a mean age of 7.1 years (SD=1.

Factors affecting duration of post-surgical orthodontics in the Surgery First/Early Approach: A retrospective study.

Background: Surgery First Approach (SFA) and Surgery Early (SE) are considered promising alternatives, compared to the conventional three-stages orthodontic-surgical approach, for treatment of dento-maxillofacial deformities. However, many features need further study, like the role of the orthodontist. Aim of the study was to analyse the clinical characteristics of patients who underwent SFA and SE, and if differences in duration of orthodontics could be influenced by clinical features.

Comparing Distal-Jet with Dental Anchorage to Distal-Jet with Skeletal Anchorage: A Prospective Parallel Cohort Study.

The use of traditional intra-oral devices in maxillary molar distalization is not without undesirable consequences. The aim of the present study was to compare the miniscrew-supported distal-jet appliance to a traditional distal-jet appliance by evaluating the amount of upper first molar distalization and the dentoalveolar side effects. Data of 600 subjects visited at the orthodontic unit of Sapienza University of Rom were analyzed.

Dental and skeletal features in subjects with missing maxillary lateral incisors: a case control retrospective study.

Background: The aim of this study was to investigate the relationship between missing maxillary lateral incisors and the mesio-distal (MD) diameters of the teeth. Occlusal and skeletal characteristics of the patients have been analyzed.

Methods: Seventy-nine patients were included in the study (permanent dentition, mean age: 13.

Psychological and Physical Distress in Italian People during COVID-19 Pandemic: One Year Later.

The aim of this study was to evaluate the major life changes that Italian people experienced after one year of the COVID-19 pandemic. We assessed the psychological and physical impact of COVID-19 within one year of the pandemic situation, and its possible correlation with the positive COVID-19 trend in the Italian region. We invited Italian people to complete a cross-sectional, online survey within a three-week period from 14 March to 4 April 2021.

Periodontal results of different therapeutic approaches (open vs. closed technique) and timing evaluation (< 2 year vs. > 2 year) of palatal impacted canines: a systematic review.

Background: This review evaluates, as a primary outcome, which surgical technique (open vs. closed) and which type of material used for the auxiliaries (elastic vs. metallic) were preferable in terms of periodontal results during the treatment of palatal-impacted canines.

Comparative Evaluation of Esthetic and Structural Aspects in Class II Functional Therapy. A Case-Control Retrospective Study.

To compare the skeletal, dental, and esthetic changes produced by three functional devices, Fränkel-2 appliance (FR-2), Twin Block (TB), and Occlus-o-Guide (O-o-G), for the treatment of Class II malocclusion. : Sixty-five patients with Class II Division 1 malocclusion were divided into three groups and were analyzed through cephalometric analysis of skeletal, dental, and esthetic variables before and after treatment. The first group of 23 patients (F: 9; M: 14; mean age: 10.

Periodontal evaluation of palatally impacted maxillary canines treated by closed approach with ultrasonic surgery and orthodontic treatment: a retrospective pilot study.

Aim of this study is the evaluation of the periodontal status of impacted canines treated by closed approach with ultrasonic surgery and orthodontic treatment compared with contralateral spontaneously erupted teeth. The periodontal conditions of the teeth adjacent to the canines (lateral incisors and first premolar) were also considered. 17 patients (9 females and 8 males; mean age: 15.

Comparision of profile macro-estethic perception among orthodontists, dentistry students, orthodontic patients and surgical orthodontic patients.

Background: The patient's needs should guide the orthodontist in choosing the most appropriate therapy. The purpose of the present survey was to compare the esthetic perception of the facial profile by orthodontists (O), dentistry students (DS), orthodontic patients (OP) and surgical-orthodontic patients (SOP) and to evaluate the influence of gender, age and level of study.

Material And Methods: A facial profile photograph of a young female was taken and twelve modified images were made, altering the position of the jaws in protrusion and in retrusion.

Uprighting Impacted Mandibular Second Molar Using a Skeletal Anchorage: A Case Report.

The aim of this case report is to present an innovative combined orthodontic-surgical technique to disimpact mandibular second molar (MM2) using an orthodontic miniscrew and an elastic chain. The impact on the Oral health-related quality of life (OHRQoL) was also evaluated. Using the present techinique, it is possible to expose the impacted tooth, insert a self-drilling miniscrew in the retromolar area, and remove the bud of third mandibular molar.

Computer-guided palatal canine disimpaction: a technical note.

Aim: To present a minimally invasive approach to solve the impaction of palatal canines using computer-guided orthodontic miniscrews.

Materials And Methods: Miniscrew-supported appliances for palatal canine disimpaction are performed with CAD/CAM technology. With adequate software, it is possible to match the STL files of the dental arch with the DICOM images of the maxilla, previously transformed into STL files.

Relationship between upper lateral incisors anomalies and palatal displaced canine: a case-control retrospective study.

Background: An observational case-control study was designed to retrospectively assess the association among sex, skeletal and dental variables and the and the palatal maxillary canine impaction.

Methods: The STROBE guidelines were followed. The records of 2195 subjects were analyzed.

The combined use of clear aligners and computer-guided piezocision: a case report with a 2-year follow-up.

Aim: An orthodontic treatment is described that combines the use of clear aligners and computer-guided piezocision to overcome the drawbacks of traditional corticotomy in accelerating orthodontic tooth movement. The relapse at the 2-year follow-up was also evaluated.

Materials And Methods: A 13-year-old male patient was selected and treated due to a molar Class II malocclusion with moderate dental crowding.

Epidemiology of Malocclusion in 3,491 Subjects Attending Public Dental Service in Rome (Italy): Evaluation of the Orthodontic Treatment Need Index.

Aim: The objective of this epidemiological survey is to investigate the dental-skeletal features of subjects attending the Public Dental Service in Unità Operativa Complessa (UOC) (Orthodontic Department of "La Sapienza University of Rome") and compare them with the existing body of evidence obtained from other surveys. Accordingly, the Index of Orthodontic Treatment Need (IOTN) was employed, in order to achieve a common framework to allow the shaping of public health prevention practices.

Materials And Methods: A sample of 3,491 subjects in the Orthodontic Department of "La Sapienza-University of Rome" (UOC) was evaluated with the adoption of IOTN to define malocclusion severity.

Whole exome sequencing in an Italian family with isolated maxillary canine agenesis and canine eruption anomalies.

Objective: The aim of this study was the clinical and molecular characterization of a family segregating a trait consisting of a phenotype specifically involving the maxillary canines, including agenesis, impaction and ectopic eruption, characterized by incomplete penetrance and variable expressivity.

Design: Clinical standardized assessment of 14 family members and a whole-exome sequencing (WES) of three affected subjects were performed. WES data analyses (sequence alignment, variant calling, annotation and prioritization) were carried out using an in-house implemented pipeline.