Publications by authors named "Rosalie V DePaola"

Article Synopsis
  • About 8% of the human genome consists of human endogenous retroviral elements (HERVs), remnants of ancient viruses integrated into our DNA over millions of years.
  • Most HERVs are now silenced due to mutations and epigenetic changes, but they were once thought to be "junk DNA" and are now recognized for their important roles, particularly in embryonic development and immune tolerance.
  • The abnormal expression of HERVs has been linked to various diseases, highlighting their evolutionary significance and potential for future research insights.
View Article and Find Full Text PDF

Study Design: Retrospective comparative study.

Objective: Whereas smoking has been shown to affect the fusion rates for patients undergoing an anterior cervical discectomy and fusion (ACDF), the relationship between smoking and health-related quality of life outcome measurements after an ACDF is less clear. The purpose of this study was to evaluate whether smoking negatively affects patient outcomes after an ACDF for cervical degenerative pathology.

View Article and Find Full Text PDF

Background: In areas where the prevalence of soil-transmitted helminthiasis (STH) is >20%, the World Health Organization (WHO) recommends that deworming medication be given periodically to preschool-age children. To reduce risk of choking-related deaths in children <3 years old, WHO recommends that deworming tablets be crushed and given with water. Little is known about how widely this is practiced or its effectiveness.

View Article and Find Full Text PDF