The retina of nonmammalian vertebrates has a loose myelin that enwraps the large axons of the ganglion cells in all areas, whereas that of mammals lacks myelin, with some exceptions, such as the rabbit retina, which shows compact myelin restricted to the myelinated streak. Electron microscopy studies in chicken retina showed processes of Müller cells (MCs) and oligodendrocytes enwrapping ganglion cell axons. How each of these cells contributes to chicken retina myelination and whether the MC of other myelinated retinas is involved in myelination remain unknown.
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