Publications by authors named "Rosales-Castillo J"

[F]FDG PET/TC is an emerging tool in the evaluation of inflammatory arthropathies, characterised by their insidious course and clinical overlap. It allows detection of subclinical inflammation, assessment of systemic involvement and quantification of metabolic parameters useful in early diagnosis and therapeutic monitoring. In rheumatoid arthritis, it correlates with clinical indices (Disease Activity Score), serological markers (CRP, anti-citrullinated protein antibodies) and ultrasound findings, and facilitates the identification of complications such as cardiovascular and pulmonary involvement.

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F-FDG PET/CT has been positioned over time as a useful tool in the evaluation of osteoarticular infections, overcoming conventional explorations like MRI or bone scintigraphy in some indications. Its ability to provide functional and anatomical images simultaneously and its excellent resolution contributes to a more precise and personalised approach in the treatment of osteoarticular diseases such as spondylodiscitis. In addition, it has proven valuable in patients with suspected infection that is complex to diagnose or treat, improving detection in subclinical stages.

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Article Synopsis
  • Radiopharmaceutical therapies (RPTs) using fibroblast activation protein (FAP) and FAP inhibitors (FAPIs) offer a new treatment option for patients with progressive metastatic cancers who have undergone multiple previous treatments.
  • A study involving 6 patients with various types of metastatic solid tumors showed that fractionated Bi-FAPI-46 RPT was feasible and well tolerated, with no reported adverse effects.
  • Initial results indicated mixed responses: one patient had a partial response, one had stable disease, while four experienced progressive disease, suggesting that while Bi-FAPI-46 RPT is promising, further research is needed to evaluate its effectiveness.
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A 53-year-old man with persisting increased serum prostate-specific antigen level (9.53 ng/mL) and repeated negative prostate biopsies was referred for a PET/CT with 68 Ga-PSMA-11. The PET/CT revealed focal uptake in the prostate suggestive of localized prostate cancer.

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  • An elderly man experienced shortness of breath for 2 months, with tests revealing low platelets and severe pulmonary hypertension.
  • A CT scan indicated potential issues in his pulmonary arteries, suggesting either a pulmonary embolism or artery sarcoma.
  • Further imaging suggested embolism, but surgery revealed he actually had a pulmonary artery sarcoma.
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Enterotoxigenic Escherichia coli is the most common cause of diarrhea in children younger than 5 years in the developing world. We used 16S rRNA gene sequencing, the Biolog system, and an Amplified Ribosomal DNA Restriction Analysis (ARDRA) to identify 69 enterobacteria isolated from the feces of healthy children up to 12 years old and 54 enterobacteria isolated from stool samples obtained from children up to 5 years old with diarrhea from Morelia, Michoacán, Mexico. In the diarrheic group, 18 isolates belonged to the enterotoxigenic pathotype, 1 isolate had both LT (heat labile toxin) gene and ST (heat stable toxin) gene, and 17 had the ST gene.

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The genetic diversity and population structure of Escherichia coli isolates from small-scale dairy farms were used to assess the ability of E. coli to spread within the farm environment and between neighboring farms. A total of 164 E.

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We assessed the relationships between chronic arsenic (As) exposure, human papilloma virus (HPV) contact and non-melanoma skin cancer (NMSC) by means of a dermatology clinic-based case-control study (42 cases and 48 controls) in Region Lagunera, Mexico, where chronic As poisoning is endemic. Exposure was determined through detailed history of residence in the As-contaminated area and measurement of As levels in drinking water and urine. We used a consensus epitope from the central region of L1 protein of the HPV family to determine antibodies against HPV.

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Objective: To summarize the evidence of acute health effects from exposure to particulate matter and ozone.

Material And Methods: A meta-analysis was performed using random effect models, to summarize the health effects of pollution, published in major international and Mexican journals up to June 2000.

Results: Results were given as percent increase in ten units of PM10 (microgram/m3) and ozone (ppb).

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