Young-onset dementia with Lewy Bodies presenting with apathy and alexithymia.

A diagnosis of young-onset dementia can pose a significant challenge for the clinician. We present a young patient with a very unusual presentation of Dementia with Lewy Bodies. The lack of motor symptoms and his marked apathy delayed his diagnosis.

Past, present, and prospects: Reflections 40 years on from the selective impairment of semantic memory (Warrington, 1975).

We summarize the main findings and conclusions of Warrington's (1975) paper, The Selective Impairment of Semantic memory, a neuropsychological paper that described three cases with degenerative neurological conditions [Warrington, E. K. (1975).

The role of configurality in the Thatcher illusion: an ERP study.

The Thatcher illusion (Thompson in Perception, 9, 483-484, 1980) is often explained as resulting from recognising a distortion of configural information when 'Thatcherised' faces are upright but not when inverted. However, recent behavioural studies suggest that there is an absence of perceptual configurality in upright Thatcherised faces (Donnelly et al. in Attention, Perception & Psychophysics, 74, 1475-1487, 2012) and both perceptual and decisional sources of configurality in behavioural tasks with Thatcherised stimuli (Mestry, Menneer et al.

Discriminating Thatcherised from typical faces in a case of prosopagnosia.

We report data from a prosopagnosic patient (PHD), and aged-matched control participants, from experiments where participants categorised individually presented emotional faces (experiment 1) and Thatcherised (from typical) faces (experiment 2). In experiment 2 participants also discriminated between simultaneously presented Thatcherised and typical faces. PHD was at chance categorising Thatcherised from typical faces.

Bilingual aphasia due to spontaneous acute subdural haematoma from a ruptured intracranial infectious aneurysm.

We report a case of spontaneous subdural haematoma due to ruptured intracranial infectious aneurysm, presenting with bilingual aphasia and illustrating differential language recovery. A 62-year-old right-handed bilingual gentleman, with a diagnosis of infective endocarditis, developed headache and became expressively aphasic in the English language. Three days later he was receptively and expressively aphasic in both English and Arabic.

Probabilistic reasoning in schizophrenia: a comparison of the performance of deluded and nondeluded schizophrenic patients and exploration of possible cognitive underpinnings.

Introduction: A number of studies have suggested that deluded patients show a "jumping to conclusions" reasoning style on probabilistic reasoning tasks. In order to systematically explore the cognitive underpinnings of this task, we compared deluded and nondeluded patients on a number of experimental manipulations to investigate the role of memory and task pragmatics on performance.

Methods: In Study 1, the performance of deluded and nondeluded schizophrenia patient groups was compared to nonpsychiatric controls on a battery of probabilistic reasoning tests.

Form completion across a hemianopic boundary: behindsight?

Patients with homonymous hemianopia may report the completion of forms that overlap the vertical meridian of their field defects. While previous investigations of "hemianopic completion" have variously attributed to the disorder to inattention, residual vision or unstable fixation, we believe that our investigation has controlled for such potentially confounding factors. We report patient P.

Remembering and forgetting of semantic knowledge in amnesia: a 16-year follow-up investigation of RFR.

We report our long-term follow-up investigations of RFR, a post-encephalitic case of very grave anterograde and retrograde amnesia. We also describe the results of quantitative neuroimaging of his brain injury that showed bilateral and severe reduction in the hippocampal formation and medial temporal structures with sparing of left lateral/posterior and right posterior temporal cortex. We established that RFR had a persistent severe anterograde and retrograde amnesia for personal and public events.

2D but not 3D: pictorial-depth deficits in a case of visual agnosia.

Patients with visual agnosia exhibit acquired impairments in visual object recognition, that may or may not involve deficits in low-level perceptual abilities. Here we report a case (patient DM) who after head injury presented with object-recognition deficits. He still appears able to extract 2D information from the visual world in a relatively intact manner; but his ability to extract pictorial information about 3D object-structure is greatly compromised.

Evidence for a context-sensitive word retrieval disorder in a case of nonfluent aphasia.

We describe a patient (BM) with nonfluent aphasia who presents with sparse, fragmented spontaneous speech but normal or near-normal performance on standard naming tasks. However, more detailed investigation revealed some unusual features to BM's naming: On a task involving repeated naming of a small set of targets, his performance degenerated when the targets were semantically blocked, particularly at fast rates of presentation. This semantic blocking effect was not observed in an analogous wordpicture matching task.

Is the mind a cauliflower or an onion? British insights into cognitive organization from the study of abnormal function.

Clinical and normal psychology have had a long tradition of close interaction in British psychology. The roots of this interplay may predate the development of the British Psychological Society, but the Society has encouraged and supported this line of research since its inception. One fundamental British insight has been to consider the evidence from pathology as a potential constraint on theories of normal function.