Publications by authors named "Rosa-Marie Apel"

Article Synopsis
  • * Researchers analyzed various data from IPF patients, finding elevated levels of the chemokine CXCL6, which correlates with poorer patient survival.
  • * The study suggests that CXCL6, produced by abnormal airway epithelial cells, enhances collagen production in lung fibroblasts, contributing to the pathology of IPF and highlighting a potential target for treatment.
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Objectives: The individual course of disease in idiopathic pulmonary fibrosis (IPF) is highly variable. Assessment of disease activity and prospective estimation of disease progression might have the potential to improve therapy management and indicate the onset of treatment at an earlier stage. The aim of this study was to evaluate whether regional ventilation, lung perfusion, and late enhancement can serve as early imaging markers for disease progression in patients with IPF.

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Background: Representative population-based data on the epidemiology of pulmonary non-tuberculous mycobacterial (PNTM) infections in Europe are limited. However, these data are needed in order to optimise patient care and to facilitate the allocation of healthcare resources. The aim of the present study was to investigate the current burden and the trends of PNTM infection-associated hospitalisations in Germany.

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