NOD2 gene variant is a risk factor for postoperative complications in patients with Crohn's disease: A genetic association study.

Background: Postoperative complications are relatively frequent in Crohn's disease (CD) and several risk factors have been identified. The influence of genetic factors, however is unknown.

Methods: CD patients who underwent CD-related bowel resection were identified from the "Nancy IBD cohort.

CARD8 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease.

Background And Aims: Post-operative recurrence is frequent in Crohn's disease. Genetic factors associated with post-operative recurrence remain poorly understood. Identification of genetic variants associated with repeat surgery would allow risk stratification of patients who may benefit from early aggressive therapy and/or post-operative prophylactic treatment.

Enzymatic production of bioactive docosahexaenoic acid phenolic ester.

Docosahexaenoic acid (DHA) is increasingly considered for its health benefits. However, its use as functional food ingredient is still limited by its instability. In this work, we developed an efficient and solvent-free bioprocess for the synthesis of a phenolic ester of DHA.