Impact of intraoperative frozen section analysis on outcome in oral squamous cell carcinoma.

Introduction: The research is focused on the reliability of Intraoperative Frozen Section Analysis (IFSA) to detect positive margins during surgical extirpation of Oral Squamous Cell Carcinoma (OSCC).

Material And Methods: Seventy-eight patients who were surgically treated for OSCC in Virgen de las Nieves University Hospital between 2019 and 2023 were included in the study. For all patients IFSA was performed during the surgery and, after the surgery, every sample underwent a complete histological analysis.

Controversies in the treatment of early-stage oral squamous cell carcinoma.

The treatment of early-stage oral squamous cell carcinoma (OSCC) is still a controversial issue. Thanks to the 8 edition of TNM by AJCC there is a better distinction between the stages of OSCC. However, Stages I and II still share the same treatment protocol, even if the prognosis is radically different.