Publications by authors named "Rosa M Lacy-Niebla"
[Frequency of cutaneous drug reactions in the outpatient dermatology clinic at the National Institute of Cardiology Ignacio Chávez over a ten-year period].
Arch Cardiol Mex
October 2024
Article Synopsis
- Cutaneous adverse drug reactions (ADRs) are the most common type of adverse reactions to medications, and this study focused on their epidemiology in a tertiary hospital in Mexico.
- Over a 10-year period, researchers analyzed the frequency of ADRs in 61 hospitalized patients and those attending the outpatient Dermatology Clinic, identifying common conditions like acneiform dermatitis and maculopapular exanthema, primarily linked to certain medications such as prednisone and hydroxychloroquine.
- The findings suggest that multiple medications taken simultaneously are significant risk factors for these reactions, highlighting the need for healthcare providers to improve their skills in recognizing and managing these skin-related issues to reduce risks to patient health.
Article Synopsis
- This project gathered experts to create guidelines for treating a skin condition called pediatric Mycosis fungoides (MF), which is different from how adults are treated.
- They talked about important factors that go beyond just measuring the size of the disease, like itching, how it affects daily life, and feelings of worry or embarrassment.
- The team made 10 recommendations for managing both early and advanced stages of pediatric MF, but they still need more information on how to treat the later stages properly.
Histoplasmosis is a fungal infection caused by the fungus . It can manifest in various ways, ranging from pulmonary to disseminated presentations. Most of the disseminated cases are seen in immunocompromised patients; here, we present an unusual case of an 81-year-old Mexican male with a history of cave exposure in his childhood, with 75 years of incubation period of the disease, who developed disseminated cutaneous histoplasmosis with no evident immunocompromising conditions.
View Article and Find Full Text PDFA 63-year-old woman with light skin and a history of chronic sun damage presented with a painless, pale macule on her nasal tip. A punch biopsy was performed due to concerns about skin conditions like vitiligo or morpheaform basal cell carcinoma (BCC). The biopsy confirmed a micronodular BCC, an unusual presentation, as these typically manifest as an erythematous macule or thin papule/plaque.
View Article and Find Full Text PDFBackground: Hypopigmented dermatoses, more evident in dark-skinned people, are a frequent cause of consultation. Their etiology includes a wide range of dermatoses, from benign to malignant diseases. The clinical presentation appears very similar between them, making the correct diagnoses and management a challenge.
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- CD30+ anaplastic large T-cell lymphoma is a rare, localized skin lymphoma requiring histopathological analysis for diagnosis.
- A study over 24 years at Hospital General "Dr. Manuel Gea González" identified only nine patients with this condition, highlighting its rarity.
- The findings suggest that the prognosis depends on the clinical stage, with early treatment leading to better outcomes.
Introduction: T-cell lymphoid dyscrasia is a group of different, infrequent, epitheliotropic inflammatory dermatosis that precede cutaneous T-cell lymphomas. Treatment with ultraviolet radiation is safe and efficacious.
Objective: To describe responses to treatment, secondary effects and complications.
Psoriasis is triggered by several stimuli that share a systemic production of interferon (IFN)-γ and other inflammatory mediators, which are key to regulate the production of matrix metalloproteinase (MMP)-9 and its inhibitor (TIMP)-1 by cells of monocytic lineage. This study evaluates the effect of the sera of 55 patients with psoriasis and 41 non-psoriatic individuals on the production of MMP-9 and TIMP-1 in cultured monocytes from a single healthy blood donor and in U937 cells. The effect of IFN-γ stimulation was also evaluated.
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- Perineurioma is a rare, benign skin tumor that arises from perineurial cells, with two main types identified: intraneural and extraneural, the latter including the sclerosing variant often found on acral skin.
- The study analyzed eight patients (five men and five women, ages 9-66) with sclerosing perineurioma, revealing distinctive microscopic features such as proliferation of specific cell types and distinct immunohistochemistry results.
- Highlighting these cases enhances awareness of sclerosing perineurioma among healthcare professionals, aiding in the differential diagnosis of skin lesions on acral areas.
Background: Psoriasis is a chronic inflammatory disease associated with increased cardiovascular risk. Metabolic syndrome (MS) is a significant predictor of cardiovascular events.
Objective: To assess the prevalence of MS in a Mexican population with psoriasis.
Background: Onychomycosis is multifactorial in origin. Studies have suggested an autosomal dominant pattern of inheritance and human leukocyte antigen DR4 (HLA-DR4) has been shown to protect against onychomycosis in an Ashkenazi Jewish population.
Aim: This study investigates HLA class II association in a Mexican Mestizo population with Trichophyton rubrum onychomycosis.
An 80-year-old man presented with a localized tumor of the right occipital scalp. The tumor was a 1-cm, bright red-purple, ulcerated, and crusted exophytic nodule on a smooth base (Figure 1). The lesion had grown asymptomatically over 18 months except for profuse bleeding induced by minimal trauma.
View Article and Find Full Text PDFCongenital generalized terminal hypertrichosis is a rare disease, especially when associated with gingival hyperplasia. Congenital hypertrichosis can be a clinical feature of several syndromes, so these patients must be studied by a multidisciplinary team that should include a dermatologist, geneticist, psychologist, odontologist, and an endocrinologist. We report a 7-year-old girl with congenital generalized hypertrichosis and gingival hyperplasia, and analyze the clinical approach, differential diagnosis, and treatment.
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