Publications by authors named "Rosa M Jimenez-Alvarado"
ATR1 A1166C (rs5186), FII G20210A (rs1799963), FV G1691A (rs6025), FXIII 97G > T (rs11466016) and MTHFR A1298C (rs1801131) polymorphisms and the risk of ST-elevation myocardial infarction in young Mexican individuals.
Mol Biol Rep
January 2024
Article Synopsis
- A study investigated the link between specific genetic polymorphisms and ST elevation Myocardial Infarction in young Mexican individuals, involving 350 patients under 45 and 350 matched controls.
- The A1166C polymorphism was found to significantly increase the risk of Myocardial Infarction, while G20210A, G1691A, 97G > T, and A1298C did not show a similar association.
- Other factors like dyslipidemia, hypertension, smoking, and family history were also linked to increased risks, indicating that genetic variations might contribute to early cardiovascular issues, but more research is needed on gene interactions.
Genetic Variants Associated with High Susceptibility of Premature Ischemic Stroke.
J Renin Angiotensin Aldosterone Syst
December 2023
Background: Several polymorphisms had been associated with an increased risk of ischemic stroke, but results are inconclusive. The aim of this study was to examine the association between AGTR1 A1166C and TSP-1 N700S polymorphisms and ischemic stroke in a young Mexican population.
Methods: In a case-control study, 250 patients ≤ 45 years of age with ischemic stroke and 250 controls matched by age and gender were included.
Objective: To examine the contribution the polymorphisms G20210A, G1691A and G10976A in the coagulation factors FII, FV, FVII, respectively; Glu298Asp and C677T in eNOS and 5,10 MTHFR in young Mexican population with cerebral infarction (CI).
Methods: 224 patients ≤ 45 years of age with CI and 224 controls matched by age and gender were recruited from 2006 and 2014. The polymorphisms were determined by polymerase chain reaction-restriction fragment length polymorphism.
: The renin-angiotensin system plays an important role in the regulation of blood pressure and the development of coronary artery disease. The aim was to examine the association of the insertion deletion in the angiotensin-converting enzyme gene, M235T and T174M polymorphisms in the angiotensinogen gene with ST elevation acute myocardial infarction (STEAMI) in young Mexican population. We analyzed 242 unrelated patients with STEAMI 45 or less years of age, admitted to a cardiovascular intense care unit, and 242 individuals without STEAMI matched by age and sex, recruited from January 2006 and June 2013.
View Article and Find Full Text PDFObjective: To ascertain the efficacy and safety of two chemotherapy regimens, one designed for adults and the other for children, in adolescent patients with acute lymphoblastic leukemia (ALL).
Methods: Between 2001-2006, we included patients aged 15-25, with de novo, Phi(-) ALL, without initial central nervous system (CNS) infiltration. Twenty patients received a chemotherapy regimen designed for children with high-risk ALL (LALIN) and twenty a regimen for adults (LALA).