Publications by authors named "Rosa M Gonzalez"
Article Synopsis
- The paper examines the decline in road accidents in Spain over the past decade, attributing this change to three main factors: institutional (like the Penalty Point System), technological advancements in vehicle safety, and macroeconomic conditions (such as the Great Recession and rising fuel prices).
- The Penalty Point System, introduced in 2006, is noted as a key factor in reducing fatal accidents, although it does not significantly impact non-fatal accidents.
- Technological improvements in vehicle safety play a considerable role in the decrease of accidents, with their positive effects recognized since the late 1990s, highlighting the importance of both economic conditions and safety measures in influencing road safety trends.
Purpose: To compare direct morphologic measurements with the ones deduced from functional tests.
Methods: A total of 111 normal eyes (examined twice) and 112 consecutive eyes with suspected or confirmed glaucoma were analyzed using Spark strategy (Oculus Easyfield Perimeter) and Cirrus optical coherence tomography (OCT). The threshold values were used to deduce the thickness of the retinal nerve fiber layer (RNFL) in 25 sectors.
Background: Research is an essential activity for improving quality and efficiency in healthcare. The objective of this study was to train nurses from the public Basque Health Service (Osakidetza) in critical appraisal, promoting continuous training and the use of research in clinical practice.
Methods: This was a prospective pre-post test study.
Purpose: The purpose of this work is to design a rapid perimetric strategy to provide averaged results.
Methods: We designed a simulation examination model using the distribution frequency of local deviations or defects, based on a retrospective study of 90,335 examinations performed in a glaucoma department.
Results: Threshold deviation from normal age-adjusted values of 6 points representative of the main areas of glaucomatous visual field allowed estimating the real mean deviation (MD) with a correlation coefficient r=0.
Pattern recognition receptors and receptors for pro-inflammatory cytokines provide critical signals to drive the development of protective immunity to infection. Therefore, counter-regulatory pathways are required to ensure that overwhelming inflammation harm host tissues. Previously, we showed that lipoxins modulate immune response during infection, restraining inflammation during infectious diseases in an Aryl hydrocarbon receptor (AhR)/suppressors of cytokine signaling (SOCS)2-dependent-manner.
View Article and Find Full Text PDFPurpose: To evaluate the specificity of the Threshold Noiseless Trend program (TNT), designed to measure progression in visual fields, using four procedures.
Materials And Methods: A. In 63 eyes with ocular hypertension, whose last examination showed no perimetric or morphological defects, we performed a mean of 7.
Background/aims: To determine the structure-function relationship throughout the different stages of glaucoma.
Subjects: 228 controls and 1007 suspected, early, moderate, or advanced glaucomas. In controls, Pearson coefficient of variation (PCV) of standard automated perimetry mean sensitivity (SAP-MS) and global mean retinal nerve fibre layer thickness (RNFL, Heidelberg Retina Tomograph) were calculated.
Background: To compare the ability of Glaucoma Progression Analysis (GPA) and Threshold Noiseless Trend (TNT) programs to detect visual-field deterioration.
Methods: Patients with open-angle glaucoma followed for a minimum of 2 years and a minimum of seven reliable visual fields were included. Progression was assessed subjectively by four masked glaucoma experts, and compared with GPA and TNT results.
Background: D-003 and policosanol (CAS 557-61-9), specific and distinct mixtures of high molecular weight primary aliphatic acids and alcohols, respectively, have shown to inhibit lipid peroxidation in vivo, but comparative studies between their effects on lipid peroxidation processes had not been conducted before.
Objective: To compare the effects of D-003 and policosanol on markers of lipid peroxidation in vivo in rats.
Methods: Male Wistar rats were distributed into 9 groups: a control group treated with acacia gum/water vehicle, 4 with policosanol and 4 with D-003, both treatments at 5, 25, 100 and 250 mg/kg.
Aim: To investigate whether oral treatment with D-004, a lipid extract of the Cuban royal palm fruit, produces antioxidant effects in the prostate tissue of normal and testosterone (T)-treated rats.
Methods: In our first experiment, normal rats were distributed into five groups: one group treated with the vehicle and four groups treated with D-004 (100, 200, 400 or 800 mg/kg). In our second experiment, rats were randomized into five groups: a negative control group and four T-injected groups.
Nursing research and the prevention of infectious diseases among vulnerable populations.
Annu Rev Nurs Res
November 2007
Racial and ethnic minorities, women and infants, youth, and other special needs populations have been found to be disproportionately affected by infectious disease morbidity and mortality, particularly Human Immunodeficiency Syndrome/Acquired Immunodeficiency Syndrome (HIV/AIDS) and other sexually transmitted diseases (STDs). Being a vital component of the health care delivery system, nurses play an important role in improving the health of these vulnerable populations. Twenty-six studies reporting results from evaluations of prevention strategies targeting HIV/AIDS and other STDs among vulnerable populations were reviewed.
View Article and Find Full Text PDFPurpose: Analyze the stability and accuracy of 3 perimetric techniques.
Methods: A total of 104 stable eyes (65 subjects) with ocular hypertension and early glaucoma [group G, mean defect = 1.08 dB, SD = 2.
Purpose: To analyze the priority of morphological and functional defects in glaucoma.
Methods: Nine-hundred seventy-three eyes of 973 subjects were examined with Heidelberg retinal tomograph (HRT II) and Octopus 311 perimeter (TOP strategy). These included 72 controls (C), 659 early and suspect open angle glaucoma (ESG) with perimetric mean defect (MD) lower than 6 dB, and 242 confirmed moderate and advanced glaucomas (AG) with perimetric MD>or=6 dB.
Objective: The objective of the Syphilis Elimination Project was to decrease the incidence of syphilis in the Hispanic community of Baltimore City through a culturally appropriate health initiative.
Design: Both qualitative and quantitative methods were used in the study design. Surveillance data were used to collect testing information.
Background: D-004, a lipid extract of the fruit of Roystonea regia, contains a mixture of fatty acids-mainly oleic, lauric, palmitic, and myristic acids, with oleic acid being among the most abundant-that has been found to reduce the risk for prostatic hyperplasia (PH) induced with testosterone (T) in rats. The pharmacokinetic profile of D-004 has not been reported.
Objective: The objective of this study in rats was to assess plasma levels, tissue distribution, and excretion of total radioactivity (TR) after single-dose administration of oral D-004 radiolabeled with ((3)H)-oleic acid, as a surrogate for the pharmacokinetics of D-004.
Background: D-004, a lipid extract of the fruit of the Cuban royal palm (Roystonea regia), has been found to reduce prostatic hyperplasia (PH) induced with testosterone (T), but not PH induced with dihydrotestosterone (DHT), in rodents, suggesting the inhibition of prostate 5α-reductase activity.
Objectives: The aims of this study were to assess whether D-004 inhibits prostate 5α-reductase activity in vitro and to examine the effects of D-004 on enzyme kinetics.
Methods: This experimental study was conducted at the Pharmacology Department, Center of Natural Products, National Center for Scientific Research, Havana, Cuba.
Purpose: To compare the diagnostic abilities of the standard bracketing strategy (BR) and a fast strategy, the tendency-oriented perimetry (TOP).
Methods: Seventy-seven controls and 91 eyes from patients with glaucoma were analyzed with the strategies TOP and BR. Sensitivity (Se), specificity (Sp), the area under the receiver operating characteristic (ROC) curve (AC) and the optimum cutoff value (CO) were calculated for the visual field indices mean defect (MD), the square root of the loss variance (sLV) and the number of pathological points (NPP).
Background: Policosanol is a mixture of very-long-chain aliphatic alcohols purified from sugar cane wax with cholesterol-lowering effects, whose main component is octacosanol. Scarce data about the metabolism of octacosanol and the other fatty alcohols composing policosanol have been published.
Methods: Human fibroblasts were cultured in presence of (3)H-octacosanol during 0.
Purpose: To evaluate the diagnostic ability of a new perimetric procedure in glaucoma.
Methods: Pulsar perimeter shows white circular sinusoidal grating patterns with decreasing amplitude, 5 degrees in diameter, 500 msec in duration in 66 locations. The stimuli scale combines spatial resolution and contrast.
Background: Even though 86% of adult Latinos have a usual source of care, there is a paucity of literature on primary care-based interventions to promote cancer prevention and control in this population. This systematic review examines published primary care-based cancer control interventions that included Latinos.
Methods: MEDLINE, the Cochrane Registry, and EMBASE were searched from January 1985 to January 2003.
Background: D-003 is a mixture of long-chain aliphatic primary acids purified from sugarcane wax with hypocholesterolaemic effects proven in rabbits and healthy volunteers; it lowers serum total cholesterol (TC) and low-density lipoprotein-cholesterol (LDL-C) and increases high-density lipoprotein-cholesterol (HDL-C). D-003 also prevents lipoprotein lipid peroxidation in experimental models.
Objective: To investigate the effects of D-003 on lipid profile and lipid peroxidation in healthy human volunteers.