Publications by authors named "Rosa Labanca"
Introduction: Exogenous haptoglobin administration may enhance plasma-free hemoglobin (pfHb) clearance during hemolysis and reduce its end-organ damage: we systematically reviewed and summarized available evidence on the use of haptoglobin as a treatment for hemolysis of any cause.
Methods: We included studies describing haptoglobin administration as treatment or prevention of hemolysis-related complications. Only studies with a control group reporting at least one of the outcomes of interest were included in the quantitative synthesis.
Background: Acute kidney injury (AKI) is a serious and common complication of cardiac surgery, for which reduced kidney perfusion is a key contributing factor. Intravenous amino acids increase kidney perfusion and recruit renal functional reserve. However, the efficacy of amino acids in reducing the occurrence of AKI after cardiac surgery is uncertain.
View Article and Find Full Text PDFObjectives: Previous studies in other settings suggested that urine output (UO) might affect NephroCheck predictive value. We investigated the correlation between NephroCheck and UO in cardiac surgery patients.
Design: Post hoc analysis of a multicenter study.
Objectives: The aim of the current study was to assess the relationship among thrombin receptor activator peptide 6 (TRAP test), adenosine-5'-diphosphate (ADP test), arachidonic acid (ASPI test), and stroke/transient ischemic attack (TIA), using the multiple electrode aggregometry (Multiplate) in patients undergoing carotid thromboendarterectomy (CEA).
Design: A retrospective study.
Setting: Vascular surgery operating rooms of a university hospital.
Article Synopsis
- Sepsis is a severe condition caused by an uncontrolled immune response to infection, which often leads to high mortality and limited treatment options beyond antibiotics.
- Recent research indicates that high doses of proton pump inhibitors like esomeprazole could potentially help regulate immune reactions in sepsis patients, improving their clinical outcomes.
- The PPI-SEPSIS trial will test this hypothesis by comparing high-dose esomeprazole to a placebo in 300 critically ill patients, focusing on its effect on organ dysfunction and other health metrics over 10 days.
Objective: To compare the outcomes of patients receiving del Nido solution versus any other type of cardioplegia.
Design: A systematic review and meta-analysis of randomized trials.
Setting: Cardiac operating rooms.
Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) vaccination is the world's most important strategy for stopping the pandemic. Vaccination challenges the body's immune response and can be complicated by hypersensitivity reactions. The autonomic nervous system can modulate the inflammatory immune response, therefore constituting a potential marker to characterize individuals at high risk of hypersensitivity reactions.
View Article and Find Full Text PDFBackground: Sedation protocols in patients undergoing complex endovascular aortic aneurysm repair are not fully investigated. The aim of this study was to compare a dexmedetomidine (DEX) based sedation protocol with a remifentanil-based sedation protocol.
Methods: Seventy-nine consecutive patients undergoing complex endovascular aortic repair were enrolled and retrospectively analyzed.
Objective: Although endovascular repair of thoraco-abdominal aortic aneurysm (TAAA) is the treatment of choice in the high risk population that is ineligible for an open surgical approach, little is known about the association between the type of anaesthesia and complications. This study compared the short term clinical outcomes of patients undergoing the visceral step of TAAA with fenestrated endograft aortic repair (FEVAR) and branched endograft aortic repair (BEVAR) under general anaesthesia (GA) with sedation with monitored care anaesthesia (MAC).
Methods: This single centre, retrospective, observational study recruited 124 consecutive patients undergoing elective F/BEVAR from 2014 - 2021.