Poor quality of sleep in Mexican patients with type 2 diabetes and its association with lack of glycemic control.

Aims: To determine the association between sleep quality and lack of glycemic control in a Mexican population of type 2 diabetes patients.

Methods: Cross-sectional study. Two hundred two patients between 20 and 60 years old with a previous diagnosis of diabetes were included.

[Intracellular signaling mechanisms in thyroid cancer].

Background: Thyroid cancer is the most common malignancy of the endocrine system, the papillary variant accounts for 80-90% of all diagnosed cases. In the development of papillary thyroid cancer, BRAF and RAS genes are mainly affected, resulting in a modification of the system of intracellular signaling proteins known as «protein kinase mitogen-activated» (MAPK) which consist of «modules» of internal signaling proteins (Receptor/Ras/Raf/MEK/ERK) from the cell membrane to the nucleus. In thyroid cancer, these signanling proteins regulate diverse cellular processes such as differentiation, growth, development and apoptosis.