Publications by authors named "Rosa Iris Godinez-Santillan"
Characterization of Extractable and Non-Extractable Phenols and Betalains in Berrycactus () and Its Chemoprotective Effect in Early Stage of Colon Cancer In Vivo.
Rosa Iris Godínez-Santillán Aarón Kuri-García Iza Fernanda Ramírez-Pérez María Guadalupe Herrera-Hernández Santiaga Marisela Ahumada-Solórzano
Antioxidants (Basel)
September 2024
Article Synopsis
- - The study explored the bioactive compounds and antioxidant potential in extractable (EP) and non-extractable (NEP) polyphenol fractions of berrycactus (BC), identifying 33 polyphenols, some of which were new to BC.
- - Male Sprague Dawley rats were used to assess the effects of BC and its residue (BCR) on early colon cancer development induced by AOM/DSS, revealing that BC and BCR helped reduce colonic damage and aberrant crypt foci.
- - The NEP fractions, especially those treated with HCl, showed strong antioxidant activity and higher total phenolic content, indicating that these compounds could play a role in preventing early colon carcinogenesis while maintaining
Aberrant crypt foci (ACF) is the precursor lesion of colorectal carcinogenesis (CRC), one of the most common malignancies in the world. Many studies have reported that people with higher phytochemical intake are at a reduced risk of developing ACF. One example of the botanical potential of preventive plant products is (CA), commonly known as Chaya.
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