TeleCleft: Development and Evaluation of a Mobile Application for Monitoring Cleft Patients.

Objective: Development and evaluation of a mobile application for remote monitoring and guidance of pediatric patients diagnosed with cleft lip and/or palate (CL ± P) and their caregivers.

Design: This is a pilot cross-sectional, applied, and quantitative study.

Setting: The study was conducted in two tertiary care treatment centers in Brazil.

Digital resources in the monitoring of patients with cleft lip and palate: protocol for a scoping review.

Introduction: Cleft lip and/or palate (CL+/-P) is a congenital malformation affecting the lip and palate, requiring long-term treatment due to potential associated complications. For this reason, it is important for the patient to be continuously monitored and followed for health promotion and prevention, as well as improving the quality of life. The aim of this scoping review protocol is to identify and map the available evidence regarding the application of digital resources and technologies in the monitoring and follow-up of patients with CL+/-P.

Molar-incisor hypomineralization in a cohort of individuals born with cleft lip and palate.

Objective: This study aimed to investigate the frequency of molar-incisor hypomineralization (MIH) in individuals born with cleft lip and or cleft palate.

Settings And Sample: Three hundred eighty-six individuals born with cleft lip and/or palate before orthodontic treatment.

Methods: All the individuals were submitted to a clinical examination and intraoral standardized photos.

CLEFT RR- New app to Calculate Recurrence Risk in Cleft lip and Palate.

Objective: To describe the Cleft Recurrence Risk (Cleft RR) App, designed to be used on genetic counseling for cleft lip and/ or palate.

Design: A validation study, single cohort.

Setting: Tertiary care children's Hospital.

COMT rs4818 less common allele is associated with psychological and psychiatric worse indicators in a cohort of individuals born with cleft lip and palate.

Objective: Individuals born with cleft lip and palate may face difficulties in speech function, nutrition, facial aesthetics, and long-term care. These difficulties may increase the risk of psychological and psychiatric diseases. This work aimed to test if the variant allele of COMT was carried more frequently among individuals that have psychological and psychiatric outcomes within a cohort of patients born with cleft lip and palate.

Distinct Patterns of Dental Age and Chronological Age: Longitudinal Evaluation of Individuals Born with or without Oral Clefts.

Dental development is delayed in individuals born with oral clefts. The purpose of this study was to determine: (1) the proportion of individuals with severe delays in dental maturation; and (2) if there are different patterns of dental development timing, taking into consideration the chronological age of the individual.
Dental maturation was estimated by the Demirjian method in children aged seven to 12 years with and without clefts.

Risk factors for anterior open bite: A case-control study.

Background: Anterior open bite (AOB) is noteworthy because it is a complex dysplasia, and clinical studies on this malocclusion are usually epidemiological studies or experimental models with small samples and no control group, which renders the data on AOB incomplete and therefore inconclusive. The objective this study was to assess the risk factors involved in developing AOB.

Materials And Methods: A case-control study was provided with a total of 96 lateral cephalometric radiographs of male and female patients aged between 8 and 14 years were used, regardless of facial type.

Multiple Structural Microform Defects Suggest Role of Modifier Genes.

One of the biggest challenges in clinical genetics is establishing associations between specific germline mutations and the resulting spectrum of phenotypes. The careful characterization of clinical presentations continues to be a tool for establishing these genotype phenotype correlations. The authors intend, by presenting a case study, proposing that the concomitant occurrence of a combinations of mild structural anomalies in the same individual may be due to changes in genes that can be linked by related pathways.

Analysis of permanent second molar development in children born with cleft lip and palate.

Objective: The study of dental development in individuals born with cleft lip and palate (CLP) serves to determine when orthodontic intervention should start. To evaluate the permanent second molar development in children born with cleft lip and palate according to Demirjian's and Nolla's methods.

Methodology: Out of a total of 513 digital panoramic radiographs, 113 pairs of children aged 3 to 16 years were selected.

Management of Oronasal Fistulas in Patients With Cleft Lip and Palate.

Background: The oronasal fistula in cleft patients is one of the complications that can be found after primary surgeries due to a failure of healing of the surgical repair that causes the communication between the oral and nasal cavities. A number of procedures can be implemented to correct the fistula and it is not clear if a particular technique is the best to be recommended.

Objective: This study aims to systematically analyze the scientific evidence regarding the treatment of oronasal fistulas located in the lingual-alveolar and labial-alveolar regions in patients with cleft lip and palate who have undergone primary surgeries.

An analysis of third molar mineralization in Brazilian patients with cleft lip and palate.

This study investigated the third molar mineralization in patients with cleft lip and palate. From a total of 253 digital panoramic radiographs from patients with cleft lip and palate within the age range of 7-21 years, 97 radiographs were selected (cleft group). A control group was formed from same sex individuals, without malformation and chronological age matched within 30 days.

Assessment of upper airways measurements in patients with mandibular skeletal Class II malocclusion.

Objective: Mandibular Class II malocclusions seem to interfere in upper airways measurements. The aim of this study was to assess the upper airways measurements of patients with skeletal Class II malocclusion in order to investigate the association between these measurements and the position and length of the mandible as well as mandibular growth trend, comparing the Class II group with a Class I one.

Methods: A total of 80 lateral cephalograms from 80 individuals aged between 10 and 17 years old were assessed.

Facial growth evaluation of complete unilateral cleft lip and palate operated patients: a cleft reference center in Paraíba, Brazil, using the "GOSLON" yardstick.

Objectives: To evaluate the surgical outcomes of patients with complete unilateral cleft lip and palate (CUCLP) operated on by a single surgeon of the cleft reference center of the Lauro Wanderley University Hospital at the Federal University of Paraiba.

Methods: Forty-four individuals' dental casts diagnosed with CUCLP, born between 1995 and 2002, mean age of 11 years, were evaluated by three calibrated orthodontic specialists and scored by the Great Ormond Street, London and Oslo (GOSLON) yardstick on two occasions. The scores were compared with those observed in other centers around the world.