Association between telomere length and CYP19 TTTA repetition polymorphism in healthy and breast cancer-diagnosed women.

Introduction: Several studies have reported an increase in breast cancer (BC) risk when patients are carriers of the CYP19 TTA polymorphism with ≥10 repeats; moreover, it has been reported that telomere length is associated with a higher susceptibility of developing cancer.

Objective: The objective of this study was to understand the relationship between CYP19 TTTA repetition polymorphism and telomere length and its effects on serum estradiol, estrone and follicle-stimulating hormone (FSH).

Materials And Methods: A total of 180 postmenopausal healthy and 70 BC-diagnosed women were included.