Sleep and COVID-19: considerations about immunity, pathophysiology, and treatment.

The fear and uncertainty caused by the coronavirus disease 2019 (COVID-19) pandemic, threats to survival are one of the main problems of everyday life; however, mental health care must also be considered a priority. During social isolation also called self-quarantine, the restricted mobility and social contact, concern about financial resources and availability of supplies, fear of infection, questions about the duration of self-quarantine, cause anxiety, depression, stress, insomnia and reduced the quality and quantity of sleep, that may present a greater risk to the health of the general population. Sleep disorders are increasingly becoming a major health issue in modern society, and are influenced by retinal stimulation by electronic devices, as well extended and/or night shift-work, which may aggravate the systemic and lung inflammation during viral infections.

Crude oil and S500 diesel removal from seawater by polyurethane composites reinforced with palm fiber residues.

In this work, we prepared PU-composites with Australian palm residues (PR) in different contents (5, 10, 15, and 20 wt%) and granulometry (28 and 35 mesh) to improve the oil (crude oil and S500 Diesel) sorption capacity. The foams were characterized by life cycle assessment (LCA), scanning electron microscopy, oil sorption, desorption, and Langmuir, Freundlich, and Temkin sorption isotherms. LCA indicated that higher PR contents decreased the foam environmental impacts than the classical residue handling, indicating that 20 wt% PR is the better environmental option, independent of the residues granulometry.

Integrative reviews in Brazilian nursing postgraduation programs: a bibliometric study.

Objectives: to analyze the Brazilian scientific integrative review production in postgraduation nursing programs.

Methods: bibliometric design, carried out in the database of dissertations and theses of the Coordination for the Improvement of Higher Education Personnel, in October 2018.

Results: 35 dissertations and 1 thesis were found.

Quantum Advantage in the Charging Process of Sachdev-Ye-Kitaev Batteries.

The exactly solvable Sachdev-Ye-Kitaev (SYK) model has recently received considerable attention in both condensed matter and high energy physics because it describes quantum matter without quasiparticles, while being at the same time the holographic dual of a quantum black hole. In this Letter, we examine SYK-based charging protocols of quantum batteries with N quantum cells. Extensive numerical calculations based on exact diagonalization for N up to 16 strongly suggest that the optimal charging power of our SYK quantum batteries displays a superextensive scaling with N that stems from genuine quantum mechanical effects.

Needs for family caregivers of Cerebrovascular Accident survivors.

Objectives: To know the needs of family caregivers of Cerebrovascular Accident survivors.

Methods: This is a qualitative, descriptive, and exploratory study. Data were collected from 37 family caregivers of Cerebrovascular Accident survivors from a city in the interior of Bahia, through an interview using a semi-structured form, between September 2017 and March 2018, and submitted to thematic content analysis.

Design of biodegradable bi-compartmental microneedles for the stabilization and the controlled release of the labile molecule collagenase for skin healthcare.

Proteins are widely explored as therapeutic agents, but some issues remain alive in their delivery versus target tissues and organs. Especially in the case of water-labile proteins, they undergo rapid failure if not properly stored or once they have encountered the biological environment. In this framework, delivery systems can be very useful to protect such proteins both during storage and during their administration.

Impact of pharmacy-supported interventions on proportion of patients receiving non-indicated acid suppressive therapy upon discharge: A systematic review and meta-analysis.

Objective: Conduct a systematic review and meta-analysis to estimate the impact of pharmacy-supported interventions on the proportion of patients discharged from the hospital on inappropriate acid suppressive therapy (AST).

Methods: To identify studies, the following databases were systematically searched on October 14th, 2018 and repeated on September 12th, 2019: Ovid MEDLINE(R) and In-Process & Other Non-Indexed Citations and Daily, Embase.com, CINAHL, Web of Science, Cochrane CENTRAL (EBSCO), and ClinicalTrials.

Impact of Infection on Patients with Chronic Inflammatory Airway Diseases.

() is a ubiquitous and opportunistic microorganism and is considered one of the most significant pathogens that produce chronic colonization and infection of the lower respiratory tract, especially in people with chronic inflammatory airway diseases such as asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), and bronchiectasis. From a microbiological viewpoint, the presence and persistence of over time are characterized by adaptation within the host that precludes any rapid, devastating injury to the host. Moreover, this microorganism usually develops antibiotic resistance, which is accelerated in chronic infections especially in those situations where the frequent use of antimicrobials facilitates the selection of "hypermutator strain".

Evolution of Bystander Intention to Perform Resuscitation Since Last Training: Web-Based Survey.

Background: Victims of out-of-hospital cardiac arrest (OHCA) have higher survival rates and more favorable neurological outcomes when basic life support (BLS) maneuvers are initiated quickly after collapse. Although more than half of OHCAs are witnessed, BLS is infrequently provided, thereby worsening the survival and neurological prognoses of OHCA victims. According to the theory of planned behavior, the probability of executing an action is strongly linked to the intention of performing it.

Febrile young infants with abnormal urine dipstick at low risk of invasive bacterial infection.

Objectives: To develop and validate a prediction rule to identify well-appearing febrile infants aged ≤90 days with an abnormal urine dipstick at low risk of invasive bacterial infections (IBIs, bacteraemia or bacterial meningitis).

Design: Ambispective, multicentre study.

Setting: The derivation set in a single paediatric emergency department (ED) between 2003 and 2017.

The influence of PBAT content in the nanocapsules preparation and its effect in essential oils release.

Nanoencapsulation provides new alternatives for the food industry, enabling a controlled and slow release of active antimicrobial agents, such as essential oils (EO). Poly (butylene adipate-co-terephthalate) (PBAT) nanocapsules loaded with linalool EO were prepared using an extrusion method with 1, 3, and 5% w/v (PBAT to chloroform). Nanocapsules' sizes ranged from 100 to 250 nm and were spherical.

Sleep Disturbance during Infection Compromises Tfh Differentiation and Impacts Host Immunity.

Although the influence of sleep quality on the immune system is well documented, the mechanisms behind its impact on natural host immunity remain unclear. Meanwhile, it has been suggested that neuroimmune interactions play an important role in this phenomenon. To evaluate the impact of stress-induced sleep disturbance on host immunity, we used a murine model of rapid eye movement sleep deprivation (RSD) integrated with a model of malaria blood-stage infection.

Comprehensive insight into surfactant modified-PBAT physico-chemical and biodegradability properties.

This work aimed to prepare surfactant modified-PBAT (poly(butylene adipate-co-terephthalate)) sheets with superior properties to increase the PBAT applicability and be a possible solution for plastic disposal environmental problems. Three different surfactant contents (0, 1, 5, and 10 wt%) were investigated, and their effects on PBAT chemical structure, mechanical and morphological properties, wettability, and water absorption were investigated. Modified-PBAT samples showed high hydrogen bond coefficients (0.

Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF.

Background: After traumatic skeletal muscle injury, muscle healing is often incomplete and produces extensive fibrosis. The sequence of M1 and M2 macrophage accumulation and the duration of each subtype in the injured area may help to direct the relative extent of fibrogenesis and myogenesis during healing. We hypothesized that increasing the number of M1 macrophages early after traumatic muscle injury would produce more cellular and molecular substrates for myogenesis and fewer substrates for fibrosis, leading to better muscle healing.

Breast cancer survival in Brazil: How much health care access impact on cancer outcomes?

Background: Breast cancer has a high incidence and increasing mortality in Southern Brazil. The present study evaluated clinical and sociodemographic characteristics, and their association with overall survival in a private cancer center.

Methods: 1113 breast cancer patients were included in this study.

Innovative process for obtaining modified nanocellulose from soybean straw.

In the present research, soybean straw was used to prepare nanocellulose (NC) via a ball mill, in different milling times (6, 9, and 12 h) and in-situ modified with an anionic surfactant. NCs were characterized for their chemical structure, surface composition, dimension and stability, morphology, crystalline structure, and thermal stability. Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy results indicated a cellulosic structure for NCs and a physical interaction due to the electronic attractions between nanocellulose hydroxyls and surfactant end chain groups.

Lived experience of patients in ICU after cardiac surgery: A phenomenological study.

Background: Cardiac surgery (CS) patients spend a significant amount of time in the intensive care unit (ICU). This event can be very overwhelming, with an intense emotional impact, causing vulnerability and a sense of helplessness in patients. Currently, the in-depth description of the ICU stay experience from a patient's own perspective is little studied, especially in the CS setting and using a qualitative approach in Italy.

Antileishmanial activity of the essential oils of Cambess. and (DC) McLeisch leads to parasite mitochondrial damage.

is a species causative of cutaneous and anergic diffuse cutaneous leishmaniasis, treatment-resistant form, in the New World. Plants essential oils exhibit great potential as microbicide agents. We described the composition of the essential oils of two plants native from Brazil, , with geranial and neral as major constituents, and with α-bisabolol.

Global Research Alliance N O chamber methodology guidelines: Guidelines for gap-filling missing measurements.

Nitrous oxide (N O) is a potent greenhouse gas that is primarily emitted from agriculture. Sampling limitations have generally resulted in discontinuous N O observations over the course of any given year. The status quo for interpolating between sampling points has been to use a simple linear interpolation.

Circulating Metabolites as Potential Biomarkers for Neurological Disorders-Metabolites in Neurological Disorders.

There are, still, limitations to predicting the occurrence and prognosis of neurological disorders. Biomarkers are molecules that can change in different conditions, a feature that makes them potential tools to improve the diagnosis of disease, establish a prognosis, and monitor treatments. Metabolites can be used as biomarkers, and are small molecules derived from the metabolic process found in different biological media, such as tissue samples, cells, or biofluids.

Eating Duration throughout a Rotating Shift Schedule: A Case Study.

Objective: The impact of the rotation between different shifts and free days within a short period of time on the food consumption is poorly addressed in the literature. Our objective was to characterize the eating duration (ED) over 10 d of clockwise rotating and to associate it with the intake of energy and macronutrients.

Methods: Thirty male shift-workers from a mining company were evaluated over a complete rotation shift schedule of 10 consecutive days (2 d of morning shifts, 2 d of afternoon shifts, 24 h free-day, 2 d of night shifts, and three free days).

Development of bioactive films based on chitosan and Cynara cardunculus leaves extracts for wound dressings.

The development of natural based, effective and protective wound dressings associated to local treatment applied on chronic wounds, represents a major challenge nowadays. In this work chitosan-based films were prepared with different concentrations of ethanolic ultrasound assisted extracts from Cynara cardunculus leaves (EtPUAE). The physico-chemical film properties revealed that extract incorporation influences the volumetric swelling capacity and mechanical properties of the films, leading to materials with a lower fluid absorption capacity and more fragile.

Oral Surgery in Patients With Sturge-Weber Syndrome.

The Sturge-Weber syndrome (SSW) is a congenital neurocutaneous malformation, with angiomas involving the leptomeningea and facial skin. This syndrome is characterized by corticocerebral angiomatosis, cerebral calcifications, ocular affections, mental retardation, increased risk of stroke, counterlateral hemiplegia, and seizures. Another important feature of SSW is the flameus nevus on the face.

The psychosocial impact of flu influenza pandemics on healthcare workers and lessons learnt for the COVID-19 emergency: a rapid review.

Objectives: During a pandemic, healthcare workers (HCWs) are essential to the health system response. Based on our knowledge, little information is available regarding the psychosocial impact on HCWs or interventions for supporting them during pandemics. Therefore, the study aimed to assess available literature on perceived stress and psychological responses to influenza pandemics in HCWs and identify implications for healthcare practice and future research.