Publications by authors named "Rosa C Fernandes"
Aims: Astrocytic S100B and receptor for advanced glycation endproducts (RAGE) have been implicated in Parkinson׳s disease (PD) pathogenesis through yet unclear mechanisms. This study attempted to characterize S100B/mRAGE (signaling isoform) axis in a dying-back dopaminergic (DAergic) axonopathy setting, which mimics an early event of PD pathology.
Methods: C57BL/6 mice were submitted to a chronic MPTP paradigm (20 mg/kg i.