Background: Non-pharmacological interventions (NPIs) are preferred alternatives to using antipsychotic medications to manage disruptive behaviors in nursing home (NH) residents living with dementia. However, the implementation of these interventions is often complex in the NH environment. In this qualitative analysis of data from an embedded pragmatic clinical trial (ePCT) of a personalized music intervention, we describe NH-level implementation barriers and facilitators.
View Article and Find Full Text PDFTuberculosis (TB) dactylitis of the hand is a rare and challenging pathology, requiring positive bacterial identification through culture or biopsy for diagnosis. Treatment is also challenging, although it typically yields an excellent response to long-term tuberculostatic therapy. We describe a case of osteoarticular tuberculous dactylitis in a 36-year-old woman with rheumatoid arthritis (RA) and a history of lymphoma.
View Article and Find Full Text PDFWithin the framework of positive psychology, this study aims to investigate whether meaning in life, optimism and future orientation have acted together as a psychological resource in coping with a non-normative challenge such as the Covid-19 pandemic. 389 respondents participated in this study. Future time perspective, presence/search for meaning in life, life orientation and dimensions of well-being (anxiety, depression, stress and aggressive behavior) were assessed.
View Article and Find Full Text PDFBackground: Shorter courses of antimicrobial therapy have been shown to be non-inferior to longer durations for the management of several infections. However, data on critically ill patients with severe infections by multidrug-resistant Gram-negative bacteria (MDR-GNB) are scarce. In the duratiOn of theraPy in severe infecTIons by MultIdrug-reSistant gram-nEgative bacteria (OPTIMISE) trial, we assessed the non-inferiority of 7-day versus 14-day antimicrobial therapy for patients with intensive care unit (ICU)-acquired severe infections by MDR-GNB.
View Article and Find Full Text PDFIntroduction: The finger-ring test (FRT) offers a simple method to screen older adults at increased risk of sarcopenia.
Objective: To investigate the association between the FRT and lean soft tissue mass estimated by dual-energy X-ray absorptiometry (DXA), and to further elucidate the FRT as an indicator of muscle mass, while accounting for potential confounders, in a community-dwelling population.
Materials And Methods: Within this cross-sectional study 430 community-dwelling individuals aged 18 to 79 (286 women (66.
(1) Background: Residential care (RC) for children and youth should provide a holistic experience of growing up. Currently, RC homes face many challenges, highlighting the need for validated, innovative interventions. D'AR-TE is a pilot project aimed at creating an innovative intervention model for children and youth in RC, promoting protective factors through activities designed to enhance personal skills, socialization, and relationship building.
View Article and Find Full Text PDFBackground And Aim: We aimed to develop and validate a simple capsule endoscopy (CE) training assessment tool, the Capsule Endoscopy Training Assessment (CETA), and prospectively use it to analyze the learning progression achieved by participants in our CE training program.
Methods: Over a 3-year period, all participants in our CE training program completed pre-training and post-training CETA, ranging between 0% and 100%, and encompassing theoretical questions and interpretation of segmented CE videos. We compared the mean differences in overall, theoretical, and practical pre-training and post-training CETA, and assessed the influence of previous endoscopic experience (upper gastrointestinal endoscopy [UGE], colonoscopy, device-assisted enteroscopy [DAE] and CE) using generalized linear models.
Stink bugs (Hemiptera, Pentatomidae) are well known by the strong odor of the defensive compounds they release, which can mediate intra- and/or interspecific interactions. Pentatomidae is one of the largest families of Heteroptera and includes many phytophagous species that are considered pests of various crops, as well as predatory species that provide biological control. Against this background, numerous research papers in Chemical Ecology have focused on communication within this group.
View Article and Find Full Text PDFUnlabelled: Respiratory alkalosis is associated with central nervous system (CNS) diseases, drugs, lung diseases and others. Safinamide is a recent anti-parkinsonian drug with anti-dyskinetic properties and a good adjunct to L-dopa therapy during the activation period, with no significant adverse effects described. The authors present a case of a 71-year-old woman, with Parkinson's disease treated with levodopa/benserazide, safinamide, amitriptyline, sertraline and diazepam.
View Article and Find Full Text PDFNative starches have a high potential for producing capsules by electrospraying despite still being little explored as biopolymeric material. Thus, the present study aimed to investigate the electrospraying capacity of native starches from different sources (cassava, corn, wheat, and sweet potato). The concentration of starch in the polymer solutions was varied from 3 % to 10 % (w/v) to investigate the impact of both starch source and concentration on the electrospraying process.
View Article and Find Full Text PDFis the agent of onchocerciasis (river blindness) and targeted by WHO for elimination though mass drug administration with ivermectin. A small percentage of adult worms develop pleomorphic neoplasms (PN) that are positively associated with the frequency of ivermectin treatment. Worms with PN have a lower life expectancy and a better understanding about the proteins expressed in PN, and how PN affect protein expression in different tissues could help to elucidate the mechanisms of macrofilaricidal activity of ivermectin.
View Article and Find Full Text PDFRev Esp Enferm Dig
October 2024
Introduction: Deciding which patients with suspected small bowel bleeding (SSB) would benefit most from small bowel capsule endoscopy (SBCE) is challenging. Our aim was to perform an external validation of the recently developed SSB Capsule Diagnostic (Dx) score that includes 3 variables (hospital admission with overt bleeding, hemoglobin <6.4 g/dL and age <54 years) and has been shown to be potentially useful in limiting the use of SBCE in SSB low-risk patients.
View Article and Find Full Text PDFPLoS Negl Trop Dis
September 2024
Interlayer excitons in transition-metal dichalcogenide heterobilayers combine high binding energy and valley-contrasting physics with a long optical lifetime and strong dipolar character. Their permanent electric dipole enables electric-field control of the emission energy, lifetime, and location. Device material and geometry impact the nature of the interlayer excitons via their real- and momentum-space configurations.
View Article and Find Full Text PDFObjective: The purpose of this article is to present the MISMARPE technique, a new minimally invasive surgical procedure to treat maxillary transverse atresia in adult patients under local anesthesia and on an outpatient basis.
Technique Description: The technique consists of miniscrew-assisted rapid palatal expansion (MARPE) associated with a minimally invasive approach using maxillary osteotomies, latency and activation periods until the desired expansion is achieved. The present MISMARPE technique was performed in 25 consecutive cases with a success rate of 96%, yielding good skeletal outcomes with minimal trauma.
Background: When performed in unfavorable conditions, work can lead to the development of musculoskeletal disorders and decrease in work ability.
Objectives: To identify the differences between three groups of workers (professors, technicians and outsourced workers) as for the sociodemographic profile, work ability, prevalence of musculoskeletal disorders, activity restrictions, and the correlation between the presence of musculoskeletal disorders and activity restrictions with each domain of the Work Ability Index.
Methods: The sample consisted of 67 university workers assessed by a Sociodemographic Data Questionnaire, the Nordic Musculoskeletal Symptoms Questionnaire and the Work Ability Index.
Introduction: During the COVID-19 pandemic, young adults worldwide showed signs of distress as they were affected in their specific developmental tasks, including the construction of personal and professional futures.
Methods: The present study aimed to assess the situational future time perspective of Italian university students during the second pandemic wave, as measured by an constructed instrument, to explore its interaction with some dispositional traits relevant in future construction, such as optimism, sense of life, aggression, and dispositional future time perspective, and to test their effect on psychological well-being. The total sample consisted of 389 subjects (18-35 years, = 23.
We report on multi-resonance chirped distributed Bragg reflector (DBR) microcavities. These systems are employed to investigate the light-mater interaction with both intra- and inter-layer excitons of transition metal dichalcogenide (TMDC) bilayer heterostructures. The chirped DBRs consisting of SiO and SiN layers of gradually varying thickness exhibit a broad stopband with a width exceeding 600 nm.
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