Publications by authors named "Rosa Alves Targino"

Unlabelled: In this large, sham-controlled, randomized trial, we examined the efficacy of the combination of standard treatment and paraspinous lidocaine injection compared with standard therapy alone in subjects with chronic low back pain. There is little research-based evidence for the routine clinical use of paraspinous lidocaine injection for low back pain. A total of 378 subjects with nonspecific chronic low back pain were randomized to 3 groups: paraspinous lidocaine injection, analgesics, and exercises (group 1, LID-INJ); sham paraspinous lidocaine injection, analgesics, and exercises (group 2, SH-INJ); and analgesics and exercises (group 3, STD-TTR).

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Introduction: Fibromyalgia and osteoarthritis may present a relationship with the concentration of cytokines. The aim of this study was to compare the serum concentrations of IL-12p70, tumor necrosis factor, IL-10, IL-6, IL-1β, and IL-8 in patients with knee osteoarthritis and fibromyalgia.

Materials And Methods: The study included 53 women (71.

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Article Synopsis
  • The study examined refractory pain in knee osteoarthritis patients and its potential link to central nervous sensitization rather than just inflammation.
  • Sixty-two female patients transitioning to total knee replacement were found to have significantly lower pressure pain thresholds (PPT) compared to healthy controls.
  • Lower PPT levels were associated with increased pain intensity, greater disability, and diminished quality of life, highlighting the need for a broader understanding of pain management in these cases.
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Objective: To evaluate the effectiveness of acupuncture for fibromyalgia.

Methods: Fifty-eight women with fibromyalgia were allocated randomly to receive either acupuncture together with tricyclic antidepressants and exercise (n=34), or tricyclic antidepressants and exercise only (n=24). Patients rated their pain on a visual analogue scale.

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