Modern insights of nanotheranostics in the glioblastoma: An updated review.

Glioblastoma multiforme (GBM) is a highly malignant subtype of glioma, originating from the glial cells that provide support to other neurons in the brain. GBM predominantly impacts the cerebral hemisphere of the brain, with minimal effects on the cerebellum, brain stem, or spinal cord. Individuals diagnosed with GBM commonly encounter a range of symptoms, starting from auditory abnormalities to seizures.

Vinyl-functionalized polyphenolic-carbon dot-based fluorometric turn-off-on biosensor for the dual detection of mercury and cysteine and their in vivo sensing in zebrafish larvae.

The fluorometric turn-off-on biosensor was developed for the ultra-sensitive detection of mercury (Hg) and cysteine (Cys) utilizing the highly fluorescent carbon dots (CDs). Herein, the sophisticated low-temperature reflux-mediated reaction was adopted using precursors namely citric acid (CA) and polyphenolic kaempferol (KMP) by using dimethylformamide (DMF) as a solvent. The resulting CDs (i.

Ruthenium(II)-curcumin liposome nanoparticles: Synthesis, characterization, and their effects against cervical cancer.

Ruthenium complexes have increased the scope for improvement in current cancer treatment by replacing platinum-based drugs. However, to reduce metal-associated toxicity, a biocompatible flavonoid, such as curcumin, is indispensable, as it offers uncompensated therapeutic benefits through formation of complexes. In this study, we synthesized metal-based flavonoid complexes using ruthenium(II) and curcumin by adopting a convenient reflux reaction, represented as Ru-Cur complexes.

Fiber-optic biosensor based on the laccase immobilization on silica-functionalized fluorescent carbon dots for the detection of dopamine and multi-color imaging applications in neuroblastoma cells.

An efficient and cost-effective biosensor is of the great demand for the detection of the biologically significant neurotransmitter dopamine. In this context, enzymatic biosensors show excellent sensitivity and selectivity. In this study, we developed a laccase immobilized fiber-optic biosensor based on the fluorescence principle for the detection of dopamine.

Lanthanum mediated rutin yellow-fluorescent carbon dots as multifaceted sensing probes for the detection of calcium ions in melanoma and plant cells.

Calcium (Ca) as a signaling ion and intracellular second messenger plays a crucial role in living organisms for various cellular functions. In the present work, we have designed a novel yellow-fluorescent carbon dots (LERCDs) using lanthanum, ethylenediaminetetraacetic acid (EDTA), and rutin as precursors for the sensing of Ca ions. In this sense, a combination of hydrothermal and reflux methods was adopted.

Biosynthesized Highly Stable Au/C Nanodots: Ideal Probes for the Selective and Sensitive Detection of Hg Ions.

The enormous ongoing industrial development has caused serious water pollution which has become a major crisis, particularly in developing countries. Among the various water pollutants, non-biodegradable heavy metal ions are the most prevalent. Thus, trace-level detection of these metal ions using a simple technique is essential.