Study Design: A prospective randomized double blind placebo controlled trail.
Objective: To evaluate and compare the efficacy and safety of batroxobin (botropase), tranexamic acid (TXA), and their combination in reduction of perioperative blood loss in lumbar spine single level fusion surgeries.
Summary Of Background Data: Spinal surgeries are associated with significant blood loss leading to perioperative anemia and increased need for allogenic transfusion.