In vitro Synthesis, Structure Elucidation, and Antioxidant Properties of Platinum(IV)-hydrazide Complexes: Molecular Modeling of Free- Hydrazides Suggested as Potent Lipoxygenase Inhibitor.

Background: A combination of biologically active ligand and metal in one molecule may increase the activity and reduce the toxicity.

Objectives: In this study, the synthesis and characterization of platinum(IV) complexes with bioactive hydrazide ligands are discussed.

Method: Elemental analysis, conductivity measurements, and spectroscopic studies were used to elucidate the structure of complexes.

Chemistry, Alpha-glucosidase and Radical Scavenging Properties of Uranyl(VI) Hydrazide Complexes.

Background: Antioxidant, anti-inflammatory, antiviral and antitumoral activities among others are essential characteristics in the development of novel therapeutic compounds. Acid hydrazides can form complexation with certain metal ions that positively enhance these biological characteristics.

Objective: Five new complexes of uranium with hydrazide ligands were synthesized at room temperature.