Organic and inorganic equivalent models for analysis of red blood cell mechanical behaviour.

Experimental investigation into the mechanical response of red blood cells is presently impeded with the main impediments being the micro dimensions involved and ethical issues associated with in vivo testing. The widely employed alternative approach of computational modelling suffers from its own inherent limitations being reliant on precise constitutive and boundary information. Moreover, and somewhat critically, numerical computational models themselves are required to be validated by means of experimentation and hence suffer similar impediments.