The Time Scale of Shallow Convective Self-Aggregation in Large-Eddy Simulations Is Sensitive to Numerics.

Numerical simulations of the tropical mesoscales often exhibit a self-reinforcing feedback between cumulus convection and shallow circulations, which leads to the self-aggregation of clouds into large clusters. We investigate whether this basic feedback can be adequately captured by large-eddy simulations (LESs). To do so, we simulate the non-precipitating, cumulus-topped boundary layer of the canonical "BOMEX" case over a range of numerical settings in two models.

How Wind Shear Affects Trade-wind Cumulus Convection.

Motivated by an observed relationship between marine low cloud cover and surface wind speed, this study investigates how vertical wind shear affects trade-wind cumulus convection, including shallow cumulus and congestus with tops below the freezing level. We ran large-eddy simulations for an idealized case of trade-wind convection using different vertical shears in the zonal wind. Backward shear, whereby surface easterlies become upper westerlies, is effective at limiting vertical cloud development, which leads to a moister, shallower, and cloudier trade-wind layer.

Clouds and Convective Self-Aggregation in a Multimodel Ensemble of Radiative-Convective Equilibrium Simulations.

The Radiative-Convective Equilibrium Model Intercomparison Project (RCEMIP) is an intercomparison of multiple types of numerical models configured in radiative-convective equilibrium (RCE). RCE is an idealization of the tropical atmosphere that has long been used to study basic questions in climate science. Here, we employ RCE to investigate the role that clouds and convective activity play in determining cloud feedbacks, climate sensitivity, the state of convective aggregation, and the equilibrium climate.

An artificial neural network ensemble approach to generate air pollution maps.

The objective of this research is to propose an artificial neural network (ANN) ensemble in order to estimate the hourly NO concentration at unsampled locations. Spatial interpolation methods and linear regression models with regularization have been compared to perform the ensemble. The study case is based on the region of the Bay of Algeciras (Spain).

Transitions in the wintertime near-surface temperature inversion at Dome C, Antarctica.

In this work we study the dynamics of the surface-based temperature inversion over the Antarctic Plateau during the polar winter. Using 6 years of observations from the French-Italian Antarctic station Concordia at Dome C, we investigate sudden regime transitions in the strength of the near-surface temperature inversion. Here we define "near-surface" as being within the domain of the 45-m measuring tower.

Multiloculated solitary (unicameral) bone cyst in a young dog.

A 20-month-old female spayed Staffordshire Terrier (22.3 kg) presented to the Orthopedic Surgery Service at North Carolina State University Veterinary Teaching Hospital for evaluation of a 6-week history of toe-touching to nonweight-bearing lameness in the right hind limb. Radiographs of the right stifle revealed a multiloculated lytic lesion of the distal femur, with a large open lytic zone centrally, numerous osseous septations peripherally, and focal areas of cortical thinning and loss.

Towards Adaptive Grids for Atmospheric Boundary-Layer Simulations.

We present a proof-of-concept for the adaptive mesh refinement method applied to atmospheric boundary-layer simulations. Such a method may form an attractive alternative to static grids for studies on atmospheric flows that have a high degree of scale separation in space and/or time. Examples include the diurnal cycle and a convective boundary layer capped by a strong inversion.

Comprehensive genomic characterization of five canine lymphoid tumor cell lines.

Background: Leukemia/lymphoma cell lines have been critical in the investigation of the pathogenesis and therapy of hematological malignancies. While human LL cell lines have generally been found to recapitulate the primary tumors from which they were derived, appropriate characterization including cytogenetic and transcriptional assessment is crucial for assessing their clinical predictive value.

Results: In the following study, five canine LL cell lines, CLBL-1, Ema, TL-1 (Nody-1), UL-1, and 3132, were characterized using extensive immunophenotyping, karyotypic analysis, oligonucleotide array comparative genomic hybridization (oaCGH), and gene expression profiling.

Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation.

Leukemia in dogs is a heterogeneous disease with survival ranging from days to years, depending on the subtype. Strides have been made in both human and canine leukemia to improve classification and understanding of pathogenesis through immunophenotyping, yet classification and choosing appropriate therapy remains challenging. In this study, we assessed 123 cases of canine leukemia (28 ALLs, 24 AMLs, 25 B-CLLs, and 46 T-CLLs) using high-resolution oligonucleotide array comparative genomic hybridization (oaCGH) to detect DNA copy number alterations (CNAs).

Do patients in hospitals benefit from single rooms? A literature review.

In the context of growing attention for 'healing environments' and 'evidence based design' an increasing number of hospitals have decided to provide single-bedded rooms. However it remains unclear to what extent these policy decisions are based on scientific evidence. The aim of this study is to review the literature on benefits of single patient rooms for patients.

The induction and analysis of micronuclei and cell killing by ultraviolet-B radiation in human peripheral blood lymphocytes.

The DNA-damaging potential of ultraviolet-B (UVB) radiation was investigated by analyzing the frequency and origin of micronuclei (MN) in cytokinesis-blocked, binucleated (BN) peripheral blood lymphocytes (PBL) and cloning efficiencies (CE) of PBL after exposure to different fluences of UVB. In total, PBL obtained from five normal donors were investigated. The PBL from all donors showed a dose-related, linear-quadratic increase in the frequency of MN per 1000 BN cells and in the frequency of micronucleated BN cells.