The role of inflammatory miRNA-mRNA interactions in PBMCs of colorectal cancer and obesity patients.

Introduction: Inflammation is a critical hallmark in obesity and colorectal cancer (CRC). This study aimed to investigate effective microRNA (miRNA)-messenger RNA (mRNA) interactions on inflammatory networks involved in obesity and CRC.

Methods: The literature searches were applied to identify genes expression reported on peripheral blood mononuclear cells (PBMCs) and/or blood of CRC subjects and to find inflammatory miRNA  in blood samples.

Association of miRNA targetome variants in LAMC1 and GNB3 genes with colorectal cancer and obesity.

Background: Colorectal cancer (CRC) is one of the most common obesity-associated cancers. Inflammation is also considered the most important factor between obesity and CRC. This study aimed to examine miRNAs binding sites variants on inflammatory genes identified using bioinformatics and systematic approach on clinical samples that were collected from CRC patients and controls.

Quality of life outcomes in patients living with stoma.

Background: Despite efforts to maintain the intestinal tissue and treat gastrointestinal disease, a large number of patients undergo ostomy surgery each year. Using stoma reduces the patient's quality of life (QOL) greatly. Although there are approximately 3000 patients in Iran; there is little information about the impact of stoma on their QOL.

Clinical profile and post-operative lifestyle changes in cancer and non-cancer patients with ostomy.

Aim: The aim of this was to investigate some clinical profiles and lifestyle changes in stoma patients.

Background: Stoma patients experienced multiple complications due to their ostomy formation.

Patients And Methods: A cross-sectional study performed on 102 random samples of stoma patients.