Intra-synovial, compared to intra-articular morphine provides better pain relief following knee arthroscopy menisectomy.

Purpose: To evaluate the analgesic effect of morphine 1 mg administered into the synovial tissue and the outer third of the meniscus after knee arthroscopy.

Methods: In a prospective, double-blind, randomized study, 60 patients who required elective knee arthroscopy were assigned to two groups: Group A consisted of 30 patients who received a direct injection of morphine 1 mg into either the synovial tissue or the outer third of the meniscus following menisectomy. Group B consisted of 30 patients who received a direct injection of NaCl 0.