Label-Free and Real-Time Detection of Tuberculosis in Human Urine Samples Using a Nanophotonic Point-of-Care Platform.

Tuberculosis (TB) is the leading global cause of death from a single infectious agent. Registered incidence rates are low, especially in low-resource countries with weak health systems, due to the disadvantages of current diagnostic techniques. A major effort is directed to develop a point-of-care (POC) platform to reduce TB deaths with a prompt and reliable low-cost technique.

Rigorous electromagnetic analysis of dipole emission in periodically corrugated layers: the grating-assisted resonant-cavity light-emitting diode.

We study the grating-assisted light-emitting diode, an LED design for high brightness based on a resonant cavity containing one- or two-dimensionally periodically corrugated layers (grating). We give in detail a generally applicable electromagnetic analysis based on the rigorous coupled-wave theory to calculate the extraction efficiency of spontaneous emission in a periodically corrugated layer structure. This general model is then specified on the grating-assisted resonant-cavity LED, showing simulated efficiencies of more than 40%.