Apparatus for low temperature thermal desorption spectroscopy of portable samples.

An experimental setup for low temperature thermal desorption spectroscopy (TDS) integrated in an ultrahigh vacuum-chamber housing a high-end scanning probe microscope for comprehensive multi-tool surface science analysis is described. This setup enables the characterization with TDS at low temperatures (T > 22 K) of portable sample designs, as is the case for scanning probe optimized setups or high-throughput experiments. This combination of techniques allows a direct correlation between surface morphology, local spectroscopy, and reactivity of model catalysts.

Rho GDP dissociation inhibitor alpha expression correlates with the outcome of CMF treatment in invasive ductal breast cancer.

Rho-GDIalpha is an inhibitor of Rho-GTPases, which is involved in cancer progression. Little is known about its role in breast cancer progression. There is evidence, that Rho-GDIalpha may modulate drug resistance of breast cancer cells.

Cyclooxygenase-2 is a target gene of rho GDP dissociation inhibitor beta in breast cancer cells.

Rho GDP dissociation inhibitor beta (Rho-GDI beta), an inhibitor of Rho GTPases, is primarily expressed by hematopoietic cells but is also found in epithelial cancer cells. Recently, we have identified Rho-GDI beta as a target of the transcription factor Ets1. Here, we show that, in breast cancer cells, Ets1 regulates Rho-GDI beta expression and binds to the upstream region of the Rho-GDI beta gene.

[The results and tolerability of infusion cholegraphy using ioglycamide-85 (12.75 g meglumine salt in 75 ml) in comparison with the use of a hypotonic adipiodone solution (10 g meglumine salt in 100 ml)].

The quality of 96 infusion cholegraphies with isotonic Ioglycamide-85 solution and of 2,080 infusion cholegraphies with hypotonic adipiodone-50 gave equal images in 97% of the cases. Ioglycamide-85 caused side-effects in 15.6%, Adipiodone only in 1.

[In vitro studies on the development of a high-density contrast medium for double contrast of the colon].

Investigations with an electron microscope and phantom imaging studies showed, that from micro-particle barium sulphate a high-density contrast medium can be produced for double-contrast-investigations of the colon. As stabilizing agent a substance with the same physical and chemical action as 0.6 g CMC (Sodium-Carboxy-Methyl-Cellulose) per 100 g barium sulphate should be used.