Third-trimester unexplained intrauterine fetal death is associated with inherited thrombophilia.

Objective: To determine the risk of thrombophilias in women with unexplained intrauterine fetal deaths (IUFD).

Methods: All women with IUFD at 27 weeks' gestation or greater were initially assessed during a period of 26 months. Subjects with multiple pregnancies, congenital anomalies, intrauterine infection, chorioamnionitis, immune hydrops, diabetes mellitus, previous thromboembolism, and severe hypertensive disease were excluded.