[AI (ARTIFICIAL INTELLIGENCE) IN AI (ARTIFICIAL INSEMINATION)].

The article, which focuses only on the prevention of the sperm and/or the frozen embryo mix-up, will begin by elaborating on the acute need to prevent the next gamete and zygote mix-up scenario. Afterwards, it will explore the practical methods already existing and the technologies. The main chapter will suggest the possible artificial intelligence technologies in the narrow field of artificial insemination for achieving that goal.

Postpartum hemorrhage among twin pregnancies - Medically assisted versus spontaneously conceived.

Introduction: In singleton pregnancies, an increased risk of Postpartum hemorrhage (PPH) have been linked with assisted reproductive technology (ART) and abnormal placentation. It is unknown wheather such association exists in twin pregnancies conceived by Medically assisted reproduction (MAR). The aim of the current study was to compare maternal blood loss among twin pregnancies conceived by different types of MAR treatments to spontaneously conceived twins and to identify the cycle characteristics if an association exits.

Perimortem and postmortem sperm acquisition: review of clinical data.

Purpose: To provide the clinicians with the most comprehensive medical information about sperm acquisition peri/postmortem.

Methods: The review was conducted according to the PRISMA statement. MEDLINE and Cochrane databases were searched up to January 2021.

Progesterone and estrogen levels are associated with live birth rates following artificial cycle frozen embryo transfers.

Purpose: Does an association exist between serum progesterone and estradiol levels and live birth rates in artificial cycle frozen embryo transfer (AC-FET)?

Methods: Retrospective cohort study was based on prospectively collected data at a university-affiliated fertility center. Included were all cycles using an artificial endometrial preparation with estradiol hemihydrate (Estrofem, 2 mg/8 h) and vaginal progesterone (Endometrin 100 mg/8 h), autologous oocytes, and cleavage stage embryo transfers. Serum progesterone and estradiol levels were measured 14 days after FET.

Ideal lag time from ovulation to oocyte aspiration using a GnRH agonist trigger.

Background: In ART, oocyte maturation (M2) and ovulation is stimulated by a hormonal trigger. For maturation to occur, sufficient "lag time" must elapse between the trigger and aspiration, ranging from 32 to 38 hours. Premature aspiration can result in poor yields; late aspiration risks spontaneous ovulation.

The Importance of Mid-Follicular Phase Luteinizing Hormone Rise in GnRH Antagonist-Based Ovarian Stimulation for IVF.

Introduction: Previous publications examined the endocrinology of follicular stimulation, focusing on luteinizing hormone (LH) levels changes. In selected, good prognosis IVF patients, a sharp drop in LH serum level was demonstrated between cycle days 2 and 6.

Objective: The purpose of this study was to examine if this finding holds true for unselected patients.

Gonadotropin Releasing Hormone Agonist Final Oocyte Maturation and Human Chorionic Gonadotropin as Exclusive Luteal Support in Normal Responders.

Background/aims: Gonadotropin releasing hormone (GnRH) agonist triggering results in an endogenous gonadotropin flare. Although it effectively stimulates ovulation, GnRH agonist triggers results in an early luteolysis and requires modification of the luteal support. The current study aims to evaluate GnRH agonist triggering with exclusive human chorionic gonadotropin (hCG) luteal support.

Increased coagulation index as measured by Thromboelastography during ovarian stimulation for in vitro fertilization: Influence of the final oocyte maturation triggering agent.

Objective: Thromboelastography (TEG) is a viscoelastic test of hemostasis which allows measurement of the processes of clot initiation, propagation, stabilization, and dissolution in real time. In this study we aimed to evaluate the alterations in coagulation as measured by TEG during In Vitro Fertilization (IVF) stimulation cycles and to investigate whether final oocyte maturation with recombinant hCG (rhCG) versus GnRH agonist results in a different coagulation state.

Study Design: This is a prospective observational study which included fifty-three normogonadotrophic women.

A homozygous mutation of in a familial case diagnosed with polycystic ovary syndrome.

Context: PCOS is a heterogeneous condition characterized by hyperandrogenism and chronic anovulation and affects about 10% of women. Its etiology is poorly known, but a dysregulation of gonadotropin secretion is one of its hallmarks.

Objective: As the etiology of PCOS is unclear, we have performed a genome-wide analysis of a consanguineous family with three sisters diagnosed with PCOS.

Health and functioning of adolescents conceived by assisted reproductive technology.

Objective: To evaluate the general health, mental health, and cognitive ability of assisted reproductive technology (ART)-conceived adolescents.

Design: A nested case-control study within a historic cohort.

Setting: Not applicable.

Clinical benefit using sperm hyaluronic acid binding technique in ICSI cycles: a systematic review and meta-analysis.

The human oocyte is surrounded by hyaluronic acid, which acts as a natural selector of spermatozoa. Human sperm that express hyaluronic acid receptors and bind to hyaluronic acid have normal shape, minimal DNA fragmentation and low frequency of chromosomal aneuploidies. Use of hyaluronic acid binding assays in intracytoplasmic sperm injection (ICSI) cycles to improve clinical outcomes has been studied, although none of these studies had sufficient statistical power.

[ABANDONED EMBRYOS OR SURPLUS FERTILIZED OOCYTES--SEEKING THE SOLUTION FOR A FROZEN BURNING PROBLEM].

Israel is a world leader in the utilization rate of in vitro fertilization (IVF). During many IVF cycles, spare fertilized oocytes are cryopreserved. Today, thousands of fertilized oocytes, cryopreserved long ago, are stored in Israeli IVF units.

A randomized trial comparing time intervals from HCG trigger to intrauterine insemination for cycles utilizing GnRH antagonists.

Intrauterine insemination (IUI) during ovarian stimulation cycles is typically performed 36 hours after human chorionic gonadotropin (hCG) injection. We hypothesized that adjusting the time interval to IUI to better coincide with ovulation may increase pregnancy rates. Patients undergoing induction of ovulation utilizing gonadotropins and gonadotropin releasing hormone (GnRH) antagonists and IUI were divided to three groups based on the time from hCG injection to IUI: 36, 42, and 48 hours.

Lag time from ovulation trigger to oocyte aspiration and oocyte maturity in assisted reproductive technology cycles: a retrospective study.

Objective: To study the correlation between the lag time from ovulation trigger to oocyte aspiration and the proportion of metaphase II (MII) mature oocytes aspirated.

Design: Retrospective study.

Setting: Fertility and IVF center in an academic regional hospital.

Rescue intracytoplasmic sperm injection: a systematic review.

Objective: To assess the feasibility, efficacy, and safety of rescue intracytoplasmic sperm injection (ICSI) in cases of fertilization failure, using a scientific literature search.

Design: Systematic review.

Setting: Centers for reproductive care.

Haptoglobin phenotypes and in vitro fertilization treatment outcomes.

The haptoglobin (Hp) protein has been implicated in various aspects of reproduction. One possible mechanism is through its effect on angiogenesis. Angiogenesis plays a major role in follicle production.

Thrombophilia and stillbirth: possible connection by intrauterine growth restriction.

Objective: To define the association between thrombophilia and unexplained stillbirth.

Design: A case-control study.

Setting: Obstetric department in a university affiliated hospital (Ha'Emek Medical Center, Afula).

Clinical and ultrasonographic weight estimation in large for gestational age fetus.

Objective: To examine prospectively the effect on pregnancy outcome of a management protocol, that adds ultrasonographic weight estimation in fetuses suspected clinically as large.

Study Design: Prospective follow up study of all singleton deliveries during a 1 year period. All patients underwent routine clinical estimation of fetal weight.