Endometrial thickness of less than 7.5 mm is associated with obstetric complications in fresh IVF cycles: a retrospective cohort study.

Research Question: Does endometrial thickness affect the occurrence of obstetric complications in fresh IVF cycles?

Design: We conducted a retrospective cohort study that included all singleton deliveries resulting from fresh embryo transfers in a single centre between 2008 and 2014. Obstetric complications, i.e.

Short-term exposure of human ovarian follicles to cyclophosphamide metabolites seems to promote follicular activation in vitro.

How chemotherapy affects dormant ovarian primordial follicles is unclear. The 'burnout' theory, studied only in mice, suggests cyclophosphamide enhances primordial follicle activation. Using 4-hydroperoxycyclophosphamide (4hc) and phosphoramide mustard (PM), this study assessed how the active cyclophosphamide metabolites 4-hydroxycyclophosphamide (4-OHC) and PM, affect human primordial follicles.

[Allegations of sexual misconduct against physicians and possible defence strategies].

Allegations of sexual misconduct against physicians by patients, as well as their relatives, are becoming more prevalent recently. No physician is immuned against such allegations. However, several medical specialties are at an increased risk for such claims; among them are Obstetrics and Gynecology, Pediatrics, Psychiatry and Family Physicians.