Publications by authors named "Rongzhao He"
Background: Neoadjuvant therapy followed by radical surgery is recommended for locally advanced rectal cancer (LARC). But radiotherapy can cause potential adverse effects. The therapeutic outcomes, postoperative survival and relapse rates between neoadjuvant chemotherapy (N-CT) and neoadjuvant chemoradiotherapy (N-CRT) patients have rarely been studied.
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- The study aimed to examine the effectiveness of the current tumor-node-metastasis (TNM) staging system and treatment methods by analyzing survival rates of patients with stage III and IV colon cancer.
- Researchers utilized data from the SEER database and SYSU cohort, involving over 19,000 cases, and employed various statistical methods to evaluate overall survival (OS) and identify risk factors.
- Findings indicated that certain subgroups, particularly patients with T4N2b tumors, exhibited poorer survival rates compared to some stage IV patients receiving curative treatment, suggesting that current cancer treatment strategies may need improvement, especially for specific high-risk groups.