Publications by authors named "Rongyuan Liao"
Background: Previous studies have revealed the abnormalities in homotopic connectivity in schizophrenia. However, the relationship of these deficits to antipsychotic treatment in schizophrenia remains unclear. This study explored the effects of antipsychotic therapy on brain homotopic connectivity and whether the homotopic connectivity of these regions might predict individual treatment response in schizophrenic patients.
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- The study investigates how metacognitive training affects brain function in patients with schizophrenia, focusing on changes within the default-mode network (DMN) and comparing results with healthy controls.
- Forty-one schizophrenia patients underwent 8 weeks of treatment, divided into two groups: one receiving metacognitive training alongside medication, and the other receiving medication only.
- Results showed that the group receiving metacognitive training exhibited notable improvements in functional connectivity, specifically in the right posterior cingulate cortex and precuneus, compared to the medication-only group, indicating that metacognitive training positively influences brain function in schizophrenia.
Increased regional homogeneity modulated by metacognitive training predicts therapeutic efficacy in patients with schizophrenia.
Eur Arch Psychiatry Clin Neurosci
June 2021
Previous studies have demonstrated the efficacy of metacognitive training (MCT) in schizophrenia. However, the underlying mechanisms related to therapeutic effect of MCT remain unknown. The present study explored the treatment effects of MCT on brain regional neural activity using regional homogeneity (ReHo) and whether these regions' activities could predict individual treatment response in schizophrenia.
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