Web-based cognitive interventions on subjective cognitive impairment in cancer survivors: A systemic review.

Objective: Cancer survivors have experienced subjective cognitive impairment (SCI) when they received cancer diagnoses or treatments. Their psychosocial and emotional statuses were also impacted. With the advancement of web technologies, web-based cognitive interventions have been implemented in the management and the alleviation of the SCI, the psychosocial distress, and the emotional distress in cancer survivors.

DSPE-mPEG2000-Modified Podophyllotoxin Long-Circulating Liposomes for Targeted Delivery: Their Preparation, Characterization, and Evaluation.

Objective: DSPE-mPEG2000 is a phospholipid and polyethylene glycol conjugate used in various biomedical applications, including drug delivery, gene transfection, and vaccine delivery. Due to the hydrophilic and hydrophobic properties of DSPE-mPEG2000, it can serve as a drug carrier, encapsulating drugs in liposomes to enhance stability and efficacy.

Method: In this study, long-circulating podophyllotoxin liposomes (Lc-PTOX-Lps) were prepared using DSPE-mPEG2000 as a modifying material and evaluated for their pharmacokinetics and anticancer activity.

miRNAs modulate altered expression of cytochrome P450s and nicotinic acetylcholine receptor subunits conferring both metabolic and target resistance to sulfoxaflor in Nilaparvata lugens (Stål).

Understanding the insecticide resistance mechanisms and their underlying regulatory pathways is essential for pest management. Previous findings indicated that the overexpression of P450 gene, CYP6ER1, was a key mechanism for sulfoxaflor metabolic resistance in Nilaparvata lugens. However, it remains unclear whether quantitative changes in the target nicotinic acetylcholine receptors (nAChRs) contribute to sulfoxaflor resistance and the underlying regulatory mechanisms involved.

A feasibility study of a couple-based illness perception intervention for couples coping with colorectal cancer.

Purpose: As a special psychological variable, illness perception significantly affects the cancer adaptions of colorectal cancer couples. No studies focus on facilitating cancer adaption by targeting the illness perception in colorectal cancer couples. This research attempted to explore the feasibility, acceptability, and potential effectiveness of an illness perception intervention program designed for couples with colorectal cancer, guided by a self-regulation common sense model.

Deletion of protein kinase C θ attenuates hepatic ischemia/reperfusion injury and further elucidates its mechanism in pathophysiology.

Objectives: Hepatic ischemia-reperfusion (HIR) is a severe process in pathophysiology that occurs clinically in hepatectomy, and hepatic transplantations. The present study aimed to investigate the effect of PKC θ deletion against HIR injury and elucidate its mechanism in pathophysiology.

Materials And Methods: HIR injury was induced in wild-type and PKC θ deletion mice treated with or without heme.

The Congruence and Interrelationship: A Dyadic Perspective on the Subjective Cognitive Impairment in the Patients with Colorectal Cancer and Their Spousal Caregivers.

Objectives: Patients with colorectal cancer (CRC) reported experiencing subjective cognitive impairment (SCI), and their spousal caregivers perceived the patients' SCI. This cross-sectional study assessed the congruence of SCI between the patients' self-reports and the spousal caregivers' perceptions and examined the factors affecting SCI from the dyadic perspective.

Methods: A total of 200 dyads of patients with CRC and their spousal caregivers were invited to complete the survey, which evaluated the SCI, dyadic coping (DC), quality of life, anxiety, and depression for the dyads.

The Illness Perceptions and Coping Experiences of Patients with Colorectal Cancer and Their Spousal Caregivers: A Qualitative Study.

(1) Background: Illness perception (IP) is an important psychological construct for couples dealing with cancer, which impacts health outcomes and the psychological adjustment to cancer. More research is needed to explore the traits of IP and the efforts of couples coping with cancer. Thus, this study was designed to explore the coping experiences and features of the IPs of couples dealing with cancer.

Interventions strategies and their efficacy in illness perceptions in patients with cancer: A systematic review and meta-analysis.

Purposes: To identify intervention strategies for improving illness perception (IP) of cancer patients and/or family caregivers; and to examine the effects of IP interventions by meta-analysis.

Methods: A systematic search was performed to identify literature that focused on improving the IP of cancer patients and/or family caregivers from the establishment of eight databases to August 2023. Manual screening was also applied.

Visualization of the Infection and Colonization Process of Using a Green Fluorescent Protein-Tagged Isolate of .

soft rot is a widespread and destructive disease caused by that can seriously affect yield and quality. To better understand the fungal infection and colonization, we successfully created an labeled with green fluorescent protein using the -mediated transformation method. Transformants had varying fluorescence intensities, but their pathogenicity did not differ from that of the wild type.

A couple-based unmet supportive care needs intervention for colorectal cancer couples: A preliminary feasibility study.

Purpose: To support colorectal cancer couples cope with cancer, we developed a couple-based unmet supportive care needs intervention program guided by the Supportive Care Needs Framework and examined the feasibility, acceptability, and initial effects of the unmet supportive care needs program.

Methods: The design of a pre-and post-intervention study was conducted among Chinese colorectal cancer couples. The intervention was delivered in five sessions through in-person and telephone interventions combined.

A Systematic Review of Cognitive Impairment in Individuals With Colorectal Cancer.

Problem Identification: Patients with colorectal cancer (CRC) encounter varying degrees of objective and subjective cognitive impairment. The prevalence of objective and subjective cognitive impairment, factors affecting cognitive impairment, and interventions are presented in this review.

Literature Search: The CINAHL Plus®, Cochrane Library, Embase®, PsycINFO®, PubMed®, and CNKI databases were systematically searched from the time of the database's establishment to May 2023.

Identification of the metaphyseal skeletal stem cell building trabecular bone.

Skeletal stem cells (SSCs) that are capable of self-renewal and multipotent differentiation contribute to bone development and homeostasis. Several populations of SSCs at different skeletal sites have been reported. Here, we identify a metaphyseal SSC (mpSSC) population whose transcriptional landscape is distinct from other bone mesenchymal stromal cells (BMSCs).

pH/chitinase dual stimuli-responsive essential oil-delivery system based on mesoporous silica nanoparticles for control of rice blast.

Background: Owing to their surface modifiability, smart mesoporous silica nanoparticles (MSNs) can be designed to respond to plant disease-microenvironmental stimuli, thereby achieving on-demand release of active ingredients to control disease by effectively improving citral (CT) stability.

Results: A pH/chitinase dual stimuli-responsive essential oil-delivery system (CT@HMS@CH/TA) was successfully fabricated by encapsulating CT in hollow mesoporous silica (HMS), and coating with tannic acid (TA) and chitosan (CH) within HMS by using the layer-by-layer assembly technique (LbL). CT@HMS@CH/TA with an average particle size of 125.

Effect of temperature fluctuations in cold seasons on acute myocardial infarction hospitalisations in northeast China: a retrospective observational cohort study.

Objective: This study aimed to determine the potential influence of ambient temperature on the incidence of acute myocardial infarction (AMI).

Design: A retrospective observational cohort study.

Setting: Changchun, a northeastern city in China, has a temperate continental humid climate.

A pH-Responsive Essential Oil Delivery System Based on Metal-organic Framework (ZIF-8) for Preventing Fungal Disease.

Smart metal-organic framework nanocarriers that respond to microenvironmental stimuli related to plant diseases can achieve the on-demand release of active ingredients to control diseases. The plant essential oil citral (CT) has significant biological activity against most pathogens but its poor stability limits its application in the field. To improve the applicability of plant essential oils, we aimed to construct a pH responsive essential oil delivery system (CT@ZIF-8) based on the zeolitic imidazolate framework-8 in this study.

Natural product osthole can significantly disrupt cell wall integrity and dynamic balance of Fusarium oxysporum.

Dendrobium officinale Kimura et Migo is a traditional Chinese herbal medicinal plant. However, the frequent occurrence of soft rot disease (SRD) is one of the most harmful diseases in D. officinale production in recent years, which can seriously affect its yield and quality.

Molecular mechanism of Osthole against chitin synthesis of Ustilaginoidea virens based on combined transcriptome and metabolome analyses.

Rice false smut, caused by the fungus Ustilaginoidea virens, is a destructive grain disease in rice-producing areas worldwide. To reveal the action mechanism of osthole against U. virens, the mycelial morphology, differential genes and metabolites of osthole-treated U.

Improving the biocompatibility and antibacterial efficacy of silver nanoparticles functionalized with (LLRR) antimicrobial peptide.

The selection of effective antibiotics is becoming increasingly limited due to the emergence of bacterial resistance. Designing and developing nanoscale antibacterials is a strategy for effectively addressing the antibiotic crisis. In this work, AgNPs@AMP nanoparticles were synthesized to take advantage of the synergistic antibacterial activity of the (LLRR) antimicrobial peptide (AMP) and silver nanoparticles (AgNPs).

Natural Product Aloesin Significantly Inhibits Spore Germination and Appressorium Formation in .

This study aims to determine the effects of the natural product aloesin against . The results exposed that aloesin had a high inhibitory effect on appressorium formation (the EC value was 175.26 μg/mL).

Analysis of complete mitogenomes and phylogenetic relationships of and .

Fleas represent a group of paramount medical significance, subsisting on blood and acting as vectors for an array of naturally occurring diseases. These pathogens constitute essential elements within the plague biome, exerting deleterious effects on both human and livestock health. In this study, we successfully assembled and sequenced the whole mitochondrial genome of and using long-range PCR and next-generation sequencing technologies.

Visualization of the entire process of rice spikelet infection by through nondestructive inoculation.

Introduction: Rice false smut caused by , is a destructive fungal disease encountered in many rice-producing areas worldwide. To determine the process by which infects rice spikelets in the field.

Methods: The green fluorescent protein-labeled was used as an inoculum to conduct artificial inoculation on rice at the booting stage via non-destructive panicle sheath instillation inoculation.

[Spatial and temporal expression pattern of somatostatin receptor 2 in mouse].

Somatostatin (SST) is an inhibitory polypeptide hormone that plays an important role in a variety of biological processes. Somatostatin receptor 2 (SSTR2) is the most widely expressed somatostatin receptor. However, the specific cell types expressing in the tissues have not been investigated.