Activation of Toll-like receptor 2 enhances peripheral and tumor-infiltrating CD8 T cell cytotoxicity in patients with gastric cancer.

Background: Toll-like receptors (TLRs) play central roles in the initiation of innate immune response, and also control adaptive immunity activation. Thus, the aim of the study was to investigate the regulation of TLR activation to CD8 T cells has not been fully elucidated in gastric cancer (GC).

Materials And Methods: Thirty-two GC patients and twenty-three healthy controls were enrolled.