Synopsis of recent research by authors named "Rongtong Zhao"
Recent research by Rongtong Zhao focuses on the development of peptide-based strategies for protein modification, utilizing sulfonium-based chemistries for site-specific functionalization and increased stability of peptides in biological systems.
One key finding includes the successful creation of sulfonium tethered peptides that enable selective modification of protein cysteine residues, providing new avenues for therapeutic intervention in cancer treatment and other diseases.
Zhao's work also highlights the potential of cyclic peptides and methionine alkylation methods to enhance cellular uptake and bioactivity, underscoring the significance of structural modifications in designing effective peptide-based drugs.
