[CiteSpace knowledge map of research hotspots and frontiers of traditional Chinese medicine intervention in psoriasis in recent ten years].

This study aimed to investigate the development status of traditional Chinese medicine(TCM) intervention in psoriasis in recent ten years, analyze the research hotspots, and summarize the development trends to provide reference materials for scholars in this field. Taking the available literature related to the field of TCM intervention in psoriasis as the research object, the trends, contents, and source publications were statistically analyzed based on bibliometrics. The research cooperation and co-occurrence of keywords in this field were studied by the knowledge map analysis method based on CiteSpace.

Deceleration of Cropland-NO Emissions in China and Future Mitigation Potentials.

Agricultural soils are the largest anthropogenic emission source of nitrous oxide (NO). National agricultural policies have been implemented to increase crop yield and reduce nitrogen (N) losses to the environment. However, it is difficult to effectively quantify crop-specific and regional NO mitigation priorities driven by policies, due to lack of long-term, high-resolution crop-specific activity data, and oversimplified models.

Satellite-detected ammonia changes in the United States: Natural or anthropogenic impacts.

Ammonia (NH) is the most abundant alkaline component and can react with atmospheric acidic species to form aerosols that can lead to numerous environmental and health issues. Increasing atmospheric NH over agricultural regions in the US has been documented. However, spatiotemporal changes of NH concentrations over the entire US are still not thoroughly understood, and the factors that drive these changes remain unknown.

Unprecedented Migratory Bird Die-Off: A Citizen-Based Analysis on the Spatiotemporal Patterns of Mass Mortality Events in the Western United States.

Extensive, severe wildfires, and wildfire-induced smoke occurred across the western and central United States since August 2020. Wildfires resulting in the loss of habitats and emission of particulate matter and volatile organic compounds pose serious threatens to wildlife and human populations, especially for avian species, the respiratory system of which are sensitive to air pollutions. At the same time, the extreme weather (e.

A comprehensive quantification of global nitrous oxide sources and sinks.

Nitrous oxide (NO), like carbon dioxide, is a long-lived greenhouse gas that accumulates in the atmosphere. Over the past 150 years, increasing atmospheric NO concentrations have contributed to stratospheric ozone depletion and climate change, with the current rate of increase estimated at 2 per cent per decade. Existing national inventories do not provide a full picture of NO emissions, owing to their omission of natural sources and limitations in methodology for attributing anthropogenic sources.

Global soil nitrous oxide emissions since the preindustrial era estimated by an ensemble of terrestrial biosphere models: Magnitude, attribution, and uncertainty.

Our understanding and quantification of global soil nitrous oxide (N O) emissions and the underlying processes remain largely uncertain. Here, we assessed the effects of multiple anthropogenic and natural factors, including nitrogen fertilizer (N) application, atmospheric N deposition, manure N application, land cover change, climate change, and rising atmospheric CO concentration, on global soil N O emissions for the period 1861-2016 using a standard simulation protocol with seven process-based terrestrial biosphere models. Results suggest global soil N O emissions have increased from 6.

Global ammonia emissions from synthetic nitrogen fertilizer applications in agricultural systems: Empirical and process-based estimates and uncertainty.

Excessive ammonia (NH ) emitted from nitrogen (N) fertilizer applications in global croplands plays an important role in atmospheric aerosol production, resulting in visibility reduction and regional haze. However, large uncertainty exists in the estimates of NH emissions from global and regional croplands, which utilize different data and methods. In this study, we have coupled a process-based Dynamic Land Ecosystem Model (DLEM) with the bidirectional NH exchange module in the Community Multiscale Air-Quality (CMAQ) model (DLEM-Bi-NH ) to quantify NH emissions at the global and regional scale, and crop-specific NH emissions globally at a spatial resolution of 0.

"Whole Chinese angelica" microemulsion: its preparation and in vivo and in vitro evaluations.

Context: The difference between the chemical polarities of the two categories of active chemical constituents in Chinese angelica volatile oil (CAVO) and Chinese angelica water extract (CAWE) greatly limit the development and clinical application of Chinese angelica preparation.

Object: The aim of this study is to design and prepare a "whole Chinese angelica" microemulsion (WCAM) that contains both CAVO and CAWE and at the same time to evaluate it in vivo and in vitro.

Materials And Methods: CAVO and CAWE extracted from Chinese angelica were used as the oil and aqueous phases, respectively, to prepare the WCAM; its physicochemical property was observed, and its drug potency and oral bioavailability were evaluated.

Activation of Src and transformation by an RPTPα splice mutant found in human tumours.

Receptor protein tyrosine phosphatase α (RPTPα)-mediated Src activation is required for survival of tested human colon and oestrogen receptor-negative breast cancer cell lines. To explore whether mutated RPTPα participates in human carcinogenesis, we sequenced RPTPα cDNAs from five types of human tumours and found splice mutants in ∼30% of colon, breast, and liver tumours. RPTPα245, a mutant expressed in all three tumour types, was studied further.

SATB1 binds an intronic MAR sequence in human PI3kgamma in vitro.

In our previous study, an intronic MAR sequence in human PI3Kgamma gene (PIMAR) was identified using bioinformatics and biochemical methods. We used MatInspector software to identify potential binding sites for MAR-binding proteins in PIMAR. In this study, a tissue-specific MAR-binding protein (SATB1) was used to characterize the potential binding sites.