CaM kinase II isoforms are expressed at lower levels in brains of shiverer mutants.

In the mammalian brain, the hippocampus is involved in memory formation and storage and has an enriched level of Ca2+/calmodulin-dependent protein kinase type II (CaM kinase II). CaM kinase II has a number of downstream targets and is shown to play a role in memory development, axonal transport, and signaling across the synapse. The shiverer mutant mouse is a knockout lacking myelin basic protein.

The involvement of Ca(2+) gradients, Ca(2+) fluxes, and CaM kinase II in polarization and germination of Silvetia compressa zygotes.

Previous work has shown that distinct Ca(2+) gradients precede and predict the loci of germination of the zygotes of the brown alga, Silvetia compressa (J. Agardh) E. Serrão, T.