G6PD-NF-κB-HGF Signal in Gastric Cancer-Associated Mesenchymal Stem Cells Promotes the Proliferation and Metastasis of Gastric Cancer Cells by Upregulating the Expression of HK2.

Tumor-associated stromal cells have been widely recognized for their tumor-promoting capability involving paracrine signaling. However, the underlying mechanism and the effects of the molecules in the glycolysis pathway in gastric cancer-associated mesenchymal stem cells (GCMSCs) and gastric cancer cells on tumor progression remain unclear. The expression of hepatocyte growth factor (HGF) in GCMSCs and bone marrow mesenchymal stem cells (BMMSCs) was detected by enzyme-linked immunosorbent assay (ELISA).

() sp. nov. (Acari, argasidae), a new tick species from the Mongolian marmot (), Gansu province in China.

A new argasid species, belonging to the subgenus , namely, () was described for the first time based on the females, males and nymphs. The morphological features of each stage in the life cycle are unique, making identification easy, but are similar to other species of the subgenus . The new species was diagnosed by the broad rectangular tongue and triangular tongue-shaped posterior lip in the male genital apron, a shallow camerostome with definite folds and smaller mammillae with single seta mixed with larger ones in nymph and adults.

Preliminary investigation of ixodid ticks in Jiangxi Province of Eastern China.

In recent years, a large effort has been made for tick surveys for public health importance around China, especially after outbreaks of severe fever with thrombocytopenia syndrome (SFTS) occurred in humans in 2009. In this paper, the preliminary species composition and population distribution of ticks in Jiangxi Province of Eastern China is reported. Ticks were collected in three habitats (grassland, shrubs and woodland) and from nine host groups in 12 sampling sites throughout Jiangxi Province between 2011 and 2018.

Description of Haemaphysalis (Alloceraea) Kolonini sp. nov., a new species in subgenus Alloceraea Schulze (Ixodidae: Haemaphysalis) in China.

Southeastern Asia has been postulated as probably the original sites of genus Haemaphysalis, where numerous structurally advanced haemaphysalids now occur. Because of its phylogenetic and biological interest, we report the discovery of a structurally primitive new species Haemaphysalis (A.) kolonini belonging to subgenus Alloceraea from Baoshan and Weixi cities, Yunnan province, southwestern China.

Enhanced gastric cancer growth potential of mesenchymal stem cells derived from gastric cancer tissues educated by CD4 T cells.

Objectives: Gastric cancer mesenchymal stem cells (GC-MSCs) can promote the development of tumour growth. The tumour-promoting role of tumour-associated MSCs and T cells has been demonstrated. T cells as the major immune cells may influence and induce a pro-tumour phenotype in MSCs.

The genus Ixodes (Acari: Ixodidae) in China with three new record species.

Total 24 valid species belongs to 6 subgenera in genus Ixodes had been documented in China. Of them, Eschatocephalus (2 species), Scaphixodes (2 species); Partipalpiger (1 species), Pholeoixodes (3 species) Ixodiopsis (1 species) and the largest subgenus Ixodes (15 species) were involved. Fortunately, we found another 3 new record species, namely I.

Safety evaluation of exosomes derived from human umbilical cord mesenchymal stromal cell.

Background Aims: Mounting evidence shows that non-cell-based transplantation of exosomes derived from mesenchymal stromal cells (MSCs) has more potential protective and reparative effects than MSCs have. However, whether it is safe to transplant MSC exosomes into tissues is still not clear. In this study, we evaluated the safety of transplantation of exosomes derived from human umbilical cord MSCs (hucMSC exosomes).

High throughput biotechnology in traditional fermented food industry.

Traditional fermented food is not only the staple food for most of developing countries but also the key healthy food for developed countries. As the healthy function of these foods are gradually discovered, more and more high throughput biotechnologies are being used to promote the old and new industry. As a result, the microflora, manufacturing processes and product healthy function of these foods were pushed forward either in the respect of profundity or extensiveness nowadays.

Babesia microti-like rodent parasites isolated from Ixodes persulcatus (Acari: Ixodidae) in Heilongjiang Province, China.

A Babesia microti-like rodent parasite was isolated from the tick, Ixodes persulcatus, collected from the northern forest area of Heilongjiang province, China. The collected I. persulcatus were allowed to feed on specific pathogen-free SCID mice and red blood cells from the mice were used to isolate Babesia spp.

Ability of Ixodes persulcatus, Haemaphysalis concinna and Dermacentor silvarum ticks to acquire and transstadially transmit Borrelia garinii.

In China, the ability of Ixodes persulcatus, Haemaphysalis concinna and Dermacentor silvarum to transmit Borrelia spirochetes was determined under laboratory conditions. Results showed that all three tick species can acquire spirochetes by feeding on infected mice. However, the capability of the three species to maintain spirochetes was different.

Ixodes sinensis: competence as a vector to transmit the Lyme disease spirochete Borrelia garinii.

In order to determine the principal vectors of Lyme disease in South China, the capability of Ixodes sinensis to transmit Lyme disease spirochetes transstadially was estimated in the laboratory. Results suggest that I. sinensis can acquire active Lyme disease spirochetes by feeding on infected mice of Kunming strains (KM), and the positive rates of larvae and nymph I.