Multifunctional ZnO-Loaded Colloidosomes with Multiple Synergies as a UV Filter.

ZnO nanoparticles with high safety and stability are often used as active ingredients in sunscreens to protect the skin from ultraviolet rays. However, ZnO nanoparticles are easy to agglomerate, which will significantly affect the ultraviolet absorption and bacteriostatic properties, and the reactive oxygen species induced by the photocatalytic activity may result in irreversible secondary damage to the skin. Herein, the ZnO nanoparticles are dispersed uniformly on the surface of latex particles, and these composite particles are used as shell materials to construct self-assembled colloidosomes by high-gravity technology, which can improve the application properties with synergistic enrichment of the hollow structure.

Fibres-threads of intelligence-enable a new generation of wearable systems.

Fabrics represent a unique platform for seamlessly integrating electronics into everyday experiences. The advancements in functionalizing fabrics at both the single fibre level and within constructed fabrics have fundamentally altered their utility. The revolution in materials, structures, and functionality at the fibre level enables intimate and imperceptible integration, rapidly transforming fibres and fabrics into next-generation wearable devices and systems.

Asymmetric Assembly in Microdroplets: Efficient Construction of MOF Micromotors for Anti-Gravity Diffusion.

Janus-micromotors, as efficient self-propelled materials, have garnered considerable attention for their potential applications in non-agitated liquids. However, the design of micromotors is still challenging and with limited approaches, especially concerning speed and mobility in complex environments. Herein, a two-step spray-drying approach encompassing symmetrical assembly and asymmetrical assembly is introduced to fabricate the metal-organic framework (MOF) Janus-micromotors with hierarchical pores.

Hydro-meteorological factors and inflowing nutrients drive water quality in an impounded lake of China's South-to-North Water Diversion Project.

Freshwater lakes play a vital role in global hydrological and biogeochemical cycles, serving various functions and maintaining ecological balance. However, freshwater resources are more vulnerable to deterioration due to multiple stressors. Gaoyou Lake is one of the impounded lakes of the Eastern route of South-to-North Water Diversion Project in China, and as an important source of drinking water, the lake has been routinely monitored.

Efficient Construction of pH-Stimuli-Responsive Colloidosomes with High Encapsulation Efficiency.

Intelligent responsive colloidosomes have attracted increasing attention for their potential to enhance the efficacy and decrease the side effects of drugs in biomedical applications. However, a low encapsulation efficiency and complicated preparation method greatly limit their development. Herein, we report an efficient approach for the construction of pH-stimuli-responsive colloidosomes with high encapsulation efficiency by a high-gravity technology.

Greatly Intensified Guest Exchange Strategy for Highly-Efficient Activation of Metal-Organic Frameworks.

The preservation and accessibility of pores are prerequisites to the application of metal-organic frameworks (MOFs). Activation is a key step to eliciting rich features of pores, but it needs a repeated solvent-exchange process which is tedious and time/cost-consuming. Herein, a facile strategy for highly-efficient activation of MOFs utilizing rotating packed bed is proposed.

Synthesis of Nucleosides and Deoxynucleosides via Gold(I)-Catalyzed -Glycosylation of Glycosyl ()-Ynenoates.

Nucleoside analogues are widely used as anticancer and antiviral drugs. Here, we develop a highly efficient gold(I)-catalyzed -glycosylation approach for versatile synthesis of various types of nucleosides and deoxynucleosides with glycosyl ()-ynenoates as donors. The wide scope of the -glycosylation approach was demonstrated by the synthesis of 31 pyrimidine nucleosides and 8 purine nucleosides.

Three-Fluid Nozzle Spray Drying Strategy for Efficient Fabrication of Functional Colloidosomes.

Colloidosomes as Pickering emulsion microcapsules are expected to serve various applications, including encapsulation of drugs and loading of functional materials. Normally, when using colloidosomes for drug encapsulation, the latex particles as shell materials need to be mixed with drugs before the assembly process. However, this procedure may cause aggregation of latex particles, thereby resulting in disordered assembled shells or a low loading efficiency.

Stereoselective synthesis of α-glucosides with glucosyl (Z)-Ynenoates as donors.

A SPhosAuNTf-promoted DMF-modulated glycosylation approach with glycosyl (Z)-ynenoates as donors was developed for highly α-selective synthesis of various linkage types of α-glucans. The substituent groups were also found to play a significant role in the α-selective glucosylation reactions. The glycosylation approach was effectively applied to the stereospecific synthesis of the α-1,6-linked triglucoside.

CrX (X = Se, Te) monolayers as a new platform to realize robust spin filters, spin diodes and spin valves.

Two-dimensional ferromagnetic (FM) half-metals are promising candidates for advanced spintronic devices with small size and high capacity. Motivated by a recent report on controlling the synthesis of FM CrTe nanosheets, herein, to explore their potential application in spintronics, we designed spintronic devices based on CrX (X = Se, Te) monolayers and investigated their spin transport properties. We found that the CrTe monolayer based device shows spin filtering and a dual-spin diode effect when applying a bias voltage, while the CrSe monolayer is an excellent platform to realize a spin valve.

Determining heavy metal pollution in sediments from the largest impounded lake in the eastern route of China's South-to-North Water Diversion Project: Ecological risks, sources, and implications for lake management.

The eastern route of the South-to-North Water Diversion Project (ER-SNWDP) is a major human health project designed to alleviate the water scarcity in the Beijing-Tianjin-Hebei region in China. Impounded lake water security is directly related to the water diversion project effectiveness. At present, there is not a thorough understanding of the sediment heavy metals in Lake Hongze, the largest impounded lake of the ER-SNWDP.

The impact and mechanisms of the Shanghai pilot free-trade zone on the green total factor productivity of the Yangtze River Delta Urban Agglomeration.

Free-trade zones are highlands of regional development that have a radiating effect on surrounding cities. This paper uses Yangtze River Delta Urban Agglomeration (YRDUA) data from 2003 to 2018, to examine the impact of the China (Shanghai) pilot free-trade zone (SPFTZ) on green total factor productivity (GTFP) in the YRDUA. It uses the regression discontinuity (RD) method and analyzes the influence mechanism with the help of the mediating effect model.

Promising Thermoelectric Performance in Two-Dimensional Semiconducting Boron Monolayer.

A heavy element is a special character for high thermoelectric performance since it generally guarantees a low lattice thermal conductivity. Here, we unexpectedly found a promising thermoelectric performance in a two-dimensional semiconducting monolayer consisting of a light boron element. Using first-principles combined with the Boltzmann transport theory, we have shown that in contrast to graphene or black phosphorus, the boron monolayer has a low lattice thermal conductivity arising from its complex crystal of hexagonal vacancies.

NIS/TMSOTf-Promoted Glycosidation of Glycosyl -Hexynylbenzoates for Versatile Synthesis of -Glycosides and Nucleosides.

Glycosidation plays a pivotal role in the synthesis of -glycosides and nucleosides that mediate a diverse range of biological processes. However, efficient glycosidation approach for the synthesis of both -glycosides and nucleosides remains challenging in terms of glycosidation yields, mild reaction conditions, readily available glycosyl donors, and cheap promoters. Here, we report a versatile -iodosuccinimide/trimethylsilyl triflate (NIS/TMSOTf)-promoted glycosidation approach with glycosyl -hexynylbenzoates as donors for the highly efficient synthesis of -glycosides and nucleosides.

Association between serum uric acid level and endothelial dysfunction in elderly individuals with untreated mild hypertension.

Background: Endothelial dysfunction is the initial stage in atherosclerotic formation and progression and is associated with high serum uric acid (SUA) level. We hypothesized that reactive hyperemia index (RHI), which reflects endothelial function, is associated with SUA levels in elderly individuals with untreated mild hypertension.

Methods: We recruited 123 patients ≥ 60 years with untreated mild hypertension.

Gold(I)-Catalyzed Glycosylation with Glycosyl Ynenoates as Donors.

A simple and versatile glycosylation method with both armed and disarmed glycosyl ynenoates as donors is developed. Employing a gold(I) complex as catalyst with or without the assistance of TfOH, the scope of the present glycosylation protocol is very wide. The utility of the present ynenoate donors is demonstrated in the efficient synthesis of oligosaccharides via the latent-active strategy and the multiple orthogonal one-pot strategy.

Gold(I)-Catalyzed Intermolecular Rearrangement Reaction of Glycosyl Alkynoic β-Ketoesters for the Synthesis of 4--Glycosylated 2-Pyrones.

A new gold(I)-catalyzed rearrangement reaction with glycosyl alkynoic β-ketoesters as substrates is developed. The rearrangement reactions under the catalysis of PPhAuOTf proceeded smoothly to afford a range of 4--glycosylated 2-pyrones. Based on the isolation of the 4-hydroxy-2-pyrone derivative generated from the departure of the leaving group and the competitive reaction, a plausible mechanism of the gold(I)-catalyzed intermolecular rearrangement reactions is proposed.

Changes in element accumulation, phenolic metabolism, and antioxidative enzyme activities in the red-skin roots of .

Background: Red-skin root disease has seriously decreased the quality and production of (ginseng).

Methods: To explore the disease's origin, comparative analysis was performed in different parts of the plant, particularly the epidermis, cortex, and/or fibrous roots of 5-yr-old healthy and diseased red-skin ginseng. The inorganic element composition, phenolic compound concentration, reactive oxidation system, antioxidant concentrations such as ascorbate and glutathione, activities of enzymes related to phenolic metabolism and oxidation, and antioxidative system particularly the ascorbate-glutathione cycle were examined using conventional methods.

Associations between human aldosterone synthase CYP11B2 (-344T/C) gene polymorphism and antihypertensive response to valsartan in Chinese patients with essential hypertension.

Aldosterone synthase is a mitochondrial enzyme that catalyzes the conversion of 11-deoxycorticosterone to the potent mineralocorticoid aldosterone. The gene encoding aldosterone synthase, CYP11B2, is associated with essential hypertension. But if the genetic variations in aldosterone synthesis could influence the antihypertensive response to Valsartan is not clear.

Association of epithelial sodium channel β-subunit common polymorphism with essential hypertension families in a Chinese population.

The purpose of this study was to investigate whether common polymorphisms in the C-terminus of SCNN1B gene encoding the β-subunit of epithelial sodium channel are associated with essential hypertension (EH) in Chinese hypertensive families. A total of 433 subjects from 102 EH families were recruited. Biochemical and anthropometric indices and systematic screening of the C-terminus of SCNN1B were performed.

Relationship between the red cell distribution width and the one-year outcomes in Chinese patients with stable angina pectoris.

Objective: This study was undertaken to determine the relationship between the red cell distribution width (RDW) and the one year outcomes in Chinese patients with stable angina pectoris.

Methods: A total of 1,442 patients with stable angina pectoris on admission were divided into four groups according to quartiles of the baseline RDW. The relationships between the RDW and one-year cardiac mortality as well as the incidence of acute coronary syndrome (ACS) were assessed.

Interleukin-6, but not soluble adhesion molecules, predicts a subsequent mortality from cardiovascular disease in patients with acute ST-segment elevation myocardial infarction.

Inflammatory responses are an important element in the atherosclerotic process. Therefore, inflammatory markers can potentially serve as predictors of cardiovascular risk. However, the existing data are limited and controversial.

[Investigation and analysis of the prevalence and risk factors for impaired fasting glucose in outpatients with essential hypertension].

Objective: To evaluate the prevalence of impaired fasting glucose (IFG) in outpatients with essential hypertension and the influencing factors.

Methods: 1026 essential hypertensive outpatients aged 15 - 87 years [531 males and 495 females, mean age (51.6 +/- 12.

P. gingivalis and E. coli lipopolysaccharides exhibit different systemic but similar local induction of inflammatory markers.

Background: Porphyromonas gingivalis is a Gram-negative bacterium that is an important etiologic agent of human adult periodontitis. The goal of the study was to test the hypothesis that two isoforms of P. gingivalis lipopolysaccharide (PgLPS), PgLPS(1435)(/1449) and PgLPS(1690), exhibit differences in their capacity to stimulate systemic versus local responses compared to Escherichia coli lipopolysaccharide (LPS).

[A cohort study on the correlation between birth weight, simple obesity, blood lipids, blood glucose and blood pressure from childhood to adolescence].

Objective: To determine the correlation between birth weight and simple obesity, blood lipids, blood glucose and blood pressure from childhood to adolescence.

Methods: A vertical sectional survey on 193 children aged 7 - 11 years was performed in 1996. A questionnaire consisting of items on environmental factors and lifestyle, physical examination and biochemical assessment was conducted at baseline and the 9th year of follow-up.