Rationale: Uterine tumors resembling ovarian sex cord tumors (UTROSCT) with rhabdoid features are uncommon mesenchymal neoplasms exhibiting diverse histological patterns, including significant rhabdoid morphology. A thorough comprehension of their clinicopathologic features is crucial for precise diagnosis and effective management.
Patient Concerns: This study presents 4 cases of UTROSCT with rhabdoid features, diagnosed in patients aged 31 to 58.
Background: Cyclin-dependent kinase subunit 2 (CKS2) is a member of cyclin dependent kinase subfamily and the relationship between CKS2 and osteosarcoma (OS) remains to be further analyzed.
Methods: 80 OS and 41 non-tumor tissue samples were arranged to perform immunohistochemistry (IHC) to evaluate CKS2 expression between OS and non-tumor samples. The standard mean deviation (SMD) was calculated based on in-house IHC and tissue microarrays, and exterior high-throughput datasets for further verification of CKS2 expression trend in OS.
Background: Noninvasive diagnostic technologies that can dynamically monitor changes in liver inflammation are highly important for the management of chronic hepatitis B (CHB) patients and thus warrant further exploration. This study assessed the diagnostic efficacy of FibroScan for liver inflammation in CHB patients.
Methods: A total of 1185 patients were selected, and ultrasound-guided liver biopsy was performed within 1 month after the FibroScan test.
Background: CDC28 Protein Kinase Regulatory Subunit 1B (CKS1B) is a member of cyclin-dependent kinase subfamily and the relationship between CKS1B and osteosarcoma (OS) remains to be explored.
Methods: 80 OS and 41 nontumor tissue samples were arranged to conduct immunohistochemistry (IHC) to evaluate CKS1B expression between OS and nontumor samples. The standard mean deviation (SMD) was calculated based on in-house IHC and tissue microarrays and exterior high-throughput datasets for further verification of CKS1B expression in OS.
We report 10 additional cases of GLI1-altered mesenchymal tumor to further delineate its clinicopathological and molecular spectrum. There were seven males and three females with a median age of 31 years (range 1.3 ~ 75 years).
View Article and Find Full Text PDFZhonghua Bing Li Xue Za Zhi
December 2012
Objective: To investigate the clinicopathologic features of calcium pyrophosphate dihydrate crystal deposition disease (CPPD-CDD).
Methods: The clinical and pathologic profiles were retrospectively analysed in 20 cases of CPPD-CDD.
Results: CPPD-CDD was far more common in women, most frequently involving joints, especially the knees and presenting with various arthrisis.
Unlabelled: Giant cell angioblastoma (GCAB) is an extremely rare soft tissue tumor of early childhood and only five cases have been described to date. As such the clinical, pathological, and prognostic features are poorly defined. We prensent here a new case of GCAB in bone of a child aged 4-years old.
View Article and Find Full Text PDFZhonghua Bing Li Xue Za Zhi
February 2012
Zhonghua Bing Li Xue Za Zhi
October 2011
Objective: To study the clinicopathologic features and histogenesis of calcifying fibrous tumor (CFT).
Methods: The clinical manifestations, histopathologic characteristics and immunophenotype were analyzed in 11 cases of CFT.
Results: The male-to-female ratio was 5:6, with a mean age of 38 years and age range of 25 to 52 years.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
August 2011
Objective: To investigate the clinicopathological features of multiple mucosal neuromas without multiple endocrine neoplasia type IIB (non-MEN-IIB MMN).
Methods: Three cases of non-MEN-IIB MMNs were analyzed for the clinical manifestations and histopathological characteristics.
Results: All the 3 cases were females, age ranging from 30 to 45 years.
Zhonghua Bing Li Xue Za Zhi
June 2011
Zhonghua Bing Li Xue Za Zhi
March 2011
Objective: To study the clinicopathologic features of lipomatosis of nerve (NLS).
Methods: The clinical, radiologic and pathologic features were analyzed in 15 cases of NLS.
Results: There were a total of 10 males and 5 females.
Objective: to study the clinicopathological features, imaging characteristics, immunophenotypes and differential diagnosis of giant cell angioblastoma (GCAB).
Methods: a case of GCAB in the left middle-upper tibia and fibula was studied by light microscopy, X-ray and CT imaging, immunohistochemistry.
Results: X-ray and CT imaging showed a clearer lesion in the left middle-upper tibia than in the ipsilateral fibula with enlarged ostealleosis and increased inhomogeneously medullary cavity density, irregular thickening of cortical bone, local cortical default at the inner edge, soft tissue swelling around the abnormal bone.