Publications by Rongjing Shen

Publications by authors named "Rongjing Shen"

Psychopharmacology (Berl)

December 2024

Diabetic retinopathy (DR) is associated with an increased risk of psychiatric and neurological issues due to factors like inflammation and oxidative stress; Cassia seed extract is believed to have anti-inflammatory and antioxidant effects, but its compound obtusin's potential remains unclear.
This study evaluated the efficacy of obtusin on diabetic mice, monitoring health indicators and assessing effects on retinal health and inflammation over 12 weeks.
Results showed that obtusin significantly improved blood glucose, reduced oxidative stress, preserved retinal function, and targeted specific oxidative stress and inflammatory pathways, suggesting it could be an effective treatment for DR and related conditions.

J Neuropathol Exp Neurol

November 2024

Alzheimer’s disease (AD) is a brain disorder that causes memory loss and confusion over time.
NMDA receptors are important in AD because they can cause harm to brain cells when there’s too much of a chemical called glutamate.
Researchers are also looking at AMPA receptors, which help with communication between brain cells, and how problems with them might cause early signs of cognitive decline in people with AD.

Spectrochim Acta A Mol Biomol Spectrosc

May 2024

The study explored using near infrared (NIR) spectroscopy to quickly assess the quality of peach kernels, focusing on authenticity, species, origin, and amygdalin levels.
The researchers compared a portable MicroNIR spectrometer with a benchtop FT-NIR spectrometer through scanning both in situ and powdered samples.
An improved principal component analysis (IPCA) method was applied to enhance the in situ model's accuracy, resulting in significantly better prediction metrics, demonstrating that model transfer can boost portable spectrometer performance.