Publications by authors named "Rong-ying Hu"
Article Synopsis
- The study explored how Alisertib (ALS), which inhibits Aurora kinase A, affects melanoma cells.
- ALS was found to slow down cell growth (anti-proliferative), promote cell death (pro-apoptotic), and enhance cell degradation processes (pro-autophagic) by blocking p38 MAPK signaling.
- Further findings showed that combining ALS with a specific p38 MAPK inhibitor boosted the effectiveness of ALS, suggesting that ALS could be a promising treatment for melanoma.
[Effect of Doxorubicin on abcb4 Gene Expression in Zebrafish (Danio rerio) Embryos].
Sichuan Da Xue Xue Bao Yi Xue Ban
January 2016
Objective: To determine the effect of doxorubicin (DOX) on abcb4 gene expression and the role of abcb4 gene in multidrug-resistance.
Methods: Zebrafish embryos were treated with 2 mL/L DMSO, 10 μmol/L DOX and 2 mL/L DMSO+10 μmol/L DOX, respectively. The zebrafish embryos treated with Eggwater served as controls.